Cytocompatiblity of Ceramic Nanoparticles to Various Types of Cells

In this study, we investigated the cytocompatibility of ceramic nanoparticles on different types of cells. All ceramics nanoparticles investigated in this study except Copper oxide (CuO) exhibited good cytocompatibility and cell viability (90% or more) even at 20 ppm concentration. In contrast, CuO...

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Bibliographic Details
Published in:Key Engineering Materials 2016-05, Vol.696, p.234-237
Main Authors: Iwadera, Nobuki, Mutoh, Mami, Akasaka, Tsukasa, Inoue, Satoshi, Katsurayama, Tomohiko, Yoshida, Yasuhiro, Abe, Shigeaki, Morimoto, Shino, Iida, Junichiro, Nakanishi, Ko, Yawaka, Yasutaka
Format: Article
Language:English
Subjects:
Biocompatibility
CERAMICS
Confocal
COPPER OXIDE
Copper oxides
CUPRIC OXIDE
Fluorescence
Microscopy
Nanoparticles
OXIDES
Particle size
PARTICLE SIZE AND SHAPE
PARTICLES
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Summary:In this study, we investigated the cytocompatibility of ceramic nanoparticles on different types of cells. All ceramics nanoparticles investigated in this study except Copper oxide (CuO) exhibited good cytocompatibility and cell viability (90% or more) even at 20 ppm concentration. In contrast, CuO nanoparticles caused cell inflammation, and their effect depended on their particle size. Confocal fluorescence microscopy measurements indicated that some particles had penetrated into the cells. These results indicate that except CuO nanoparticles, all other ceramic nanoparticles reported herein exhibited excellent cytocompatibility even for lung epithelial cells.
ISSN:1013-9826
1662-9795
1662-9795
DOI:10.4028/www.scientific.net/KEM.696.234