Copper supported beta -cyclodextrin grafted magnetic nanoparticles as an efficient recyclable catalyst for one-pot synthesis of 1-benzyl-1H-1,2,3-triazoldibenzodiazepinone derivatives viaclick reaction

• Published in: RSC advances 2016-03, Vol.6 (34), p.28838-28843
• Main Authors: Mahdavi, Mohammad, Lijan, Hosein, Bahadorikhalili, Saeed, Ma'mani, Leila, Rashidi Ranjbar, Parviz, Shafiee, Abbas
• Format: Article
• Language: English
• Subjects: Catalysts; Chemical reactions; Copper; Derivatives; Nanoparticles; Robustness; Solvents; Synthesis (chemistry)
• ISSN: 2046-2069
• DOI: 10.1039/c5ra27275k

An efficient and recoverable copper catalyst was prepared by the immobilization of Cu into beta -cyclodextrin covalently attached to magnetic nanoparticles (denoted as [Cub-CDPIONs]). A novel and one-pot synthetic approach was introduced for the synthesis of novel 1-benzyl-1H-1,2,3-triazoldibenzodiazepinone derivatives through a click reaction using [Cub-CDPIONs] as a green catalyst. The magnetic recoverable catalyst was characterized using TEM, VSM, TGA, and FT-IR techniques. This nanocatalyst appeared efficient and robust in a multicomponent reaction for the preparation of benzodiazepinones followed by a click reaction for the synthesis of 1,2,3-triazoles in an ethanol/water mixture as solvent at room temperature under mild reaction conditions and with a facile work-up process. Interesting features including water-tolerance, robustness, efficiency, mild reaction conditions, utilization of green solvents, and simple catalyst recovery make [Cub-CDPIONs] favourable from economic and environmental points of view.