Hollow Shells Development and Characterization for Cells Carrying Purpose

Bioceramics draw attention in bone tissue engineering field since their biomimetic properties regarding bone attribute. In this context, a concept of smart bioceramics granules made of Hydroxyapatite have been set up, enhancing surface area available to body fluids containing proteins and cell adhes...

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Bibliographic Details
Published in:Key Engineering Materials 2016-05, Vol.696, p.238-242
Main Authors: Moreau, Françoise, Borget, Pascal, Daculsi, Guy, Miramond, Thomas, Fellah, Borhane
Format: Article
Language:English
Subjects:
Bioceramics
Biomedical materials
Bones
Cell adhesion
Granular materials
Granules
Implantation
Surgical implants
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Summary:Bioceramics draw attention in bone tissue engineering field since their biomimetic properties regarding bone attribute. In this context, a concept of smart bioceramics granules made of Hydroxyapatite have been set up, enhancing surface area available to body fluids containing proteins and cell adhesion for bone forming respectively thanks to microporosities and macropore concavities. New “hollow shell” granules were developed and assessed by physico-chemical characterizations, in-vitro experiments and in-vivo implantation in comparison with classical round granules. This new original galenic formulation showed promising potential in cell carrying and osteoconduction matter.
ISSN:1013-9826
1662-9795
1662-9795
DOI:10.4028/www.scientific.net/KEM.696.238