Automated quantification of the epidermal aging process using in-vivo confocal microscopy

Reflectance confocal microscopy (RCM) is a powerful tool to visualize the skin layers at cellular resolution. The epidermal layer appears as a honeycomb pattern, whose regularity decreases with age. Our aim is to provide a method to automatically quantify the regularity of the honeycomb pattern. The...

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Bibliographic Details
Main Authors: Robic, J., Nkengne, A., Perret, B., Couprie, M., Talbot, H.
Format: Conference Proceeding
Language:English
Subjects:
Aging
Classification
Confocal
Epidermis
Honeycomb
Honeycomb construction
Image reconstruction
Image segmentation
In vivo
Microscopy
RCM
Reflectance confocal microscopy
Regularity
skin aging
Strategy
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Description
Summary:Reflectance confocal microscopy (RCM) is a powerful tool to visualize the skin layers at cellular resolution. The epidermal layer appears as a honeycomb pattern, whose regularity decreases with age. Our aim is to provide a method to automatically quantify the regularity of the honeycomb pattern. The proposed strategy relies on a cell-level supervised classification as regular or irregular using spatial information given by a prior segmentation. The aggregated scores defined by the classification results show significant correlation with chronological aging and photo-aging. Thus, our method enables practitioners to more objectively assess the quality of the epidermal layers on large cohort of subjects.
ISSN:1945-8452
DOI:10.1109/ISBI.2016.7493486