Restoring voice

Engineered vocal cords could soon replace damaged tissue In most mammals, a vocal sound begins with the vibration of paired vocal cords within the larynx. These delicate structures—more accurately called vocal folds because they resemble folded layers of fabric—can stiffen after traumatic injury, ca...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2015-11, Vol.350 (6263), p.908-909
Main Authors: Long, Jennifer L., Chhetri, Dinesh K.
Format: Article
Language:English
Subjects:
Disturbances
Genetics
Implants
Larynx
Mammals
Medicine
PERSPECTIVES
Tissue engineering
Vibration
Vocal cords
Voice
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Summary:Engineered vocal cords could soon replace damaged tissue In most mammals, a vocal sound begins with the vibration of paired vocal cords within the larynx. These delicate structures—more accurately called vocal folds because they resemble folded layers of fabric—can stiffen after traumatic injury, cancer treatment, or unknown environmental or genetic insults. Current voice medicine has limited options to repair or replace damaged vocal folds when the voice disturbance is disabling ( 1 ). A recent study by Ling et al. ( 2 ) reports a tissue engineering approach that could lead to implants that replace the unique vocal fold mucosa and restore vocalization.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.aad7695