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Relation between plasma antioxidant vitamin levels, adiposity and cardio-metabolic profile in adolescents: Effects of a multidisciplinary obesity programme

Summary Background & aims In vivo and in vitro evidence suggests that antioxidant vitamins and carotenoids may be key factors in the treatment and prevention of obesity and obesity-associated disorders. Hence, the objective of the present study was to determine the relationship between plasma li...

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Published in:Clinical nutrition (Edinburgh, Scotland) Scotland), 2017-02, Vol.36 (1), p.209-217
Main Authors: Guerendiain, Marcela, Mayneris-Perxachs, Jordi, Montes, Rosa, López-Belmonte, Gemma, Martín-Matillas, Miguel, Castellote, Ana I, Martín-Bautista, Elena, Martí, Amelia, Martínez, J. Alfredo, Moreno, Luis, Garagorri, Jesús Mª, Wärnberg, Julia, Caballero, Javier, Marcos, Ascensión, López-Sabater, M. Carmen, Campoy, Cristina
Format: Article
Language:English
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Summary:Summary Background & aims In vivo and in vitro evidence suggests that antioxidant vitamins and carotenoids may be key factors in the treatment and prevention of obesity and obesity-associated disorders. Hence, the objective of the present study was to determine the relationship between plasma lipid-soluble antioxidant vitamin and carotenoid levels and adiposity and cardio-metabolic risk markers in overweight and obese adolescents participating in a multidisciplinary weight loss programme. Methods A therapeutic programme was conducted with 103 adolescents aged 12–17 years old and diagnosed with overweight or obesity. Plasma concentrations of α-tocopherol, retinol, β-carotene and lycopene, anthropometric indicators of general and central adiposity, blood pressure and biochemical parameters were analysed at baseline and at 2 and 6 months of treatment. Results Lipid-corrected retinol ( P  
ISSN:0261-5614
1532-1983
DOI:10.1016/j.clnu.2015.11.001