Successful golimumab therapy in four patients with refractory Takayasu's arteritis

Recent studies suggested that anti-TNF-α biological therapies are effective in treating Takayasu's arteritis (TA) refractory to conventional immunosuppressive therapy. However, the efficacy of golimumab (GLM) for TA therapy is unknown. We report four women with TA who were successfully treated...

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Bibliographic Details
Published in:Modern rheumatology 2018-07, Vol.28 (4), p.712-715
Main Authors: Suematsu, Rie, Tashiro, Satoko, Ono, Nobuyuki, Koarada, Syuichi, Ohta, Akihide, Tada, Yoshifumi
Format: Article
Language:English
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Summary:Recent studies suggested that anti-TNF-α biological therapies are effective in treating Takayasu's arteritis (TA) refractory to conventional immunosuppressive therapy. However, the efficacy of golimumab (GLM) for TA therapy is unknown. We report four women with TA who were successfully treated with GLM. GLM was prescribed as induction therapy for three patients and as maintenance therapy for one patient. GLM showed therapeutic value and might be useful, together with other anti-TNF-α agents, in treating TA.
ISSN:1439-7595
1439-7609
DOI:10.3109/14397595.2015.1134393