Physical frailty in older people with severe aortic stenosis

• Published in: Aging clinical and experimental research 2016-12, Vol.28 (6), p.1081-1087
• Main Authors: Fukui, Shogo, Kawakami, Michiyuki, Otaka, Yohei, Ishikawa, Aiko, Mizuno, Katsuhiro, Tsuji, Tetsuya, Hayashida, Kentaro, Inohara, Taku, Yashima, Fumiaki, Liu, Meigen
• Format: Article
• Language: English
• Subjects: Aged, 80 and over; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - epidemiology; Aortic Valve Stenosis - physiopathology; Cardiovascular disease; Cerebrovascular Disorders - epidemiology; Comorbidity; Female; Frail Elderly - statistics & numerical data; Frailty; Geriatrics/Gerontology; Heart Function Tests - methods; Humans; Japan - epidemiology; Kidney Function Tests - methods; Male; Medicine; Medicine & Public Health; Musculoskeletal Diseases - epidemiology; Nutritional Status - physiology; Older people; Original Article; Prevalence; Reciprocity; Self destructive behavior; Severity of Illness Index
• ISSN: 1720-8319; 1594-0667; 1720-8319
• DOI: 10.1007/s40520-015-0507-0

Background Assessment of physical frailty is important among elderly with severe aortic stenosis (AS) when considering treatment. Aims We aimed to: (1) investigate the prevalence of physical frailty in older people with severe AS and (2) examine factors related to physical frailty. Methods A total of 125 consecutive elderly AS patients (mean age 84.6 ± 4.4 year) were enrolled. Physical frailty was defined as scoring ≤8 points on the short physical performance battery (SPPB). Factors likely related to physical frailty, including cardiac function, nutritional and metabolic status, kidney function, medical history, and comorbidities, were evaluated. Logistic regression analyses were used to examine which factors were related to physical frailty. Results Physical frailty was prevalent in 38.4 %. After sex and age adjusted, the following were significantly related to physical frailty: LVEF (adjusted OR per 10 % decrease: 1.39, p