Sex Effect on Obesity Indices and Metabolic Outcomes in Patients with Obese Obstructive Sleep Apnea and Type 2 Diabetes After Laparoscopic Roux-en-Y Gastric Bypass Surgery: a Preliminary Study

Background Roux-en-Y gastric bypass (RYGB) surgery is an effective therapy for obstructive sleep apnea (OSA). However, little attention has been paid to the treatment goals systematically stratified by sex. The objective of this study was to assess how sex differences affect obesity indices and meta...

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Bibliographic Details
Published in:Obesity surgery 2016-11, Vol.26 (11), p.2629-2639
Main Authors: Xu, Huajun, Zhang, Pin, Han, Xiaodong, Yu, Haoyong, Di, Jianzhong, Zou, Jianyin, Wang, Yuyu, Qian, Yingjun, Tu, Yinfang, Bao, Yuqian, Yi, Hongliang, Guan, Jian, Yin, Shankai, Jia, Weiping
Format: Article
Language:English
Subjects:
Adult
Bypass
Diabetes Mellitus, Type 2 - etiology
Diabetes Mellitus, Type 2 - metabolism
Diabetes Mellitus, Type 2 - physiopathology
Female
Gastric Bypass - methods
Humans
Laparoscopy
Male
Medicine
Medicine & Public Health
Metabolic disorders
Middle Aged
Obesity
Obesity - complications
Obesity - metabolism
Obesity - physiopathology
Obesity - surgery
Original Contributions
Sex Factors
Sexes
Sleep apnea
Sleep Apnea, Obstructive - etiology
Sleep Apnea, Obstructive - metabolism
Sleep Apnea, Obstructive - physiopathology
Sleep Apnea, Obstructive - surgery
Surgery
Weight Loss
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Summary:Background Roux-en-Y gastric bypass (RYGB) surgery is an effective therapy for obstructive sleep apnea (OSA). However, little attention has been paid to the treatment goals systematically stratified by sex. The objective of this study was to assess how sex differences affect obesity indices and metabolic outcomes after RYGB surgery. Methods A sleep questionnaire was conducted and medical histories were taken. Full-night polysomnography (PSG), anthropometric variables, and blood samples were collected. Results Thirty-five consecutive patients with OSA who underwent laparoscopic RYGB surgery were prospectively examined for at least 6 months were included in the study. Significant improvements ( p  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-016-2140-1