Pharmacological Provocation of Outflow-Tract Tachycardia in a Patient With Brugada Syndrome

Abstract We present a case of a symptomatic patient with Brugada syndrome, who had sustained right ventricular outflow tract tachycardia after pronounced exercise-induced ST segment elevation in V1 and V2 . In electrophysiological study he developed right ventricular outflow tract tachycardia provok...

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Bibliographic Details
Published in:Canadian journal of cardiology 2016-12, Vol.32 (12), p.1577.e5-1577.e7
Main Authors: Bürkle, Gerd, MD, Schäfer, Henry, MD, Marschall, Christoph, PhD, Brugada, Pedro, MD, Ehrlich, Joachim R., MD
Format: Article
Language:English
Subjects:
Ajmaline - administration & dosage
Ajmaline - adverse effects
Anti-Arrhythmia Agents - administration & dosage
Anti-Arrhythmia Agents - adverse effects
Brugada Syndrome - diagnosis
Brugada Syndrome - physiopathology
Brugada Syndrome - therapy
Cardiovascular
Catheter Ablation - methods
Electrocardiography - methods
Heart Conduction System - drug effects
Heart Conduction System - physiopathology
Humans
Male
Metaproterenol - administration & dosage
Metaproterenol - adverse effects
Middle Aged
Stimulation, Chemical
Tachycardia, Ventricular - chemically induced
Tachycardia, Ventricular - physiopathology
Tachycardia, Ventricular - prevention & control
Treatment Outcome
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Summary:Abstract We present a case of a symptomatic patient with Brugada syndrome, who had sustained right ventricular outflow tract tachycardia after pronounced exercise-induced ST segment elevation in V1 and V2 . In electrophysiological study he developed right ventricular outflow tract tachycardia provoked by combined infusion of ajmaline and orciprenaline. After ablation no further arrhythmia was provoked by pharmacological stimulation.
ISSN:0828-282X
1916-7075
DOI:10.1016/j.cjca.2016.01.026