Scleral and corneal xanthomatous inflammation in a gray mouse lemur (Microcebus murinus)

Bilateral multifocal corneal opacity was detected in a 4.5-year-old male captive gray mouse lemur (Microcebus murinus) without other clinical ocular changes. Histopathological examination revealed a severe diffuse granulomatous scleritis and focal keratitis with intralesional cholesterol, consistent...

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Bibliographic Details
Published in:Veterinary ophthalmology 2017, Vol.20 (2), p.177-180
Main Authors: Alleaume, Charline, Mrini, Meryem El, Laloy, Eve, Marchal, Julia, Aujard, Fabienne, Chahory, Sabine
Format: Report
Language:English
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Summary:Bilateral multifocal corneal opacity was detected in a 4.5-year-old male captive gray mouse lemur (Microcebus murinus) without other clinical ocular changes. Histopathological examination revealed a severe diffuse granulomatous scleritis and focal keratitis with intralesional cholesterol, consistent with xanthomatous inflammation. This is the first report of xanthomatous inflammation in a gray mouse lemur. This condition may be the result of systemic factors (lipid metabolism disorders) and/or local predisposing factors such as hemorrhage or inflammation. The pathogenesis in this case could not be fully determined. Further studies on lemurs are required for a better understanding of their lipid metabolism, as well as for diagnosing and evaluating the incidence of xanthomatous inflammation in these species.
ISSN:1463-5224
DOI:10.1111/vop.12374