Editor’s Choice-Acute versus subacute angiography in patients with non-ST-elevation myocardial infarction – the NONSTEMI trial phase I

Background: The 2015 European Society of Cardiology non-ST-elevation myocardial infarction (NSTEMI) guidelines recommend angiography within 24 h in high-risk patients with NSTEMI. An organized STEMI-like approach with pre-hospital or immediate in-hospital triage for acute coronary angiography (CAG)...

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Published in:European heart journal. Acute cardiovascular care 2017-09, Vol.6 (6), p.490-499
Main Authors: Stengaard, Carsten, Sørensen, Jacob T, Rasmussen, Martin B, Søndergaard, Hanne M, Dodt, Karen K, Niemann, Troels, Frost, Lars, Jensen, Tage, Hansen, Troels M, Riddervold, Ingunn Skogstad, Rasmussen, Claus-Henrik, Giebner, Mathias, Aarøe, Jens, Maeng, Michael, Christiansen, Evald H, Kristensen, Steen D, Bøtker, Hans E, Terkelsen, Christian J
Format: Article
Language:English
Subjects:
Aged
Coronary Angiography - methods
Decision Making
Disease Management
Electrocardiography
Female
Follow-Up Studies
Humans
Male
Non-ST Elevated Myocardial Infarction - blood
Non-ST Elevated Myocardial Infarction - diagnosis
Percutaneous Coronary Intervention
Point-of-Care Systems
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
Troponin T - blood
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Summary:Background: The 2015 European Society of Cardiology non-ST-elevation myocardial infarction (NSTEMI) guidelines recommend angiography within 24 h in high-risk patients with NSTEMI. An organized STEMI-like approach with pre-hospital or immediate in-hospital triage for acute coronary angiography (CAG) may be of therapeutic benefit but it remains unknown whether the patients can be properly diagnosed in the pre-hospital setting. We aim to evaluate whether it is feasible to diagnose patients with NSTEMI in the pre-hospital phase or immediately upon admission. Methods and results: We randomized 250 patients to either acute or subacute CAG (i.e.
ISSN:2048-8726
2048-8734
DOI:10.1177/2048872616648468