Immunoglobulin G4-positive staining of orbital lesions in thyroid eye disease: Report of two cases

We report two cases with immunoglobulin G4 (IgG4)-positive staining of orbital lesions and thyroid eye disease (TED). Case 1 was a 63-year-old male with right upper eyelid swelling due to right lacrimal gland enlargement. Case 2 was a 49-year-old male with bilateral proptosis due to multiple orbital...

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Bibliographic Details
Published in:Modern rheumatology 2018-09, Vol.28 (5), p.893-896
Main Authors: Takahashi, Yasuhiro, Takahashi, Emiko, Hiromatsu, Yuji, Kakizaki, Hirohiko
Format: Article
Language:English
Subjects:
Eye Diseases - immunology
Eye Diseases - pathology
Humans
Immunoglobulin G - immunology
Lacrimal Apparatus - immunology
Lacrimal Apparatus - pathology
Male
Middle Aged
Thyroid Gland - immunology
Thyroid Gland - pathology
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Summary:We report two cases with immunoglobulin G4 (IgG4)-positive staining of orbital lesions and thyroid eye disease (TED). Case 1 was a 63-year-old male with right upper eyelid swelling due to right lacrimal gland enlargement. Case 2 was a 49-year-old male with bilateral proptosis due to multiple orbital masses. Both the biopsied right lacrimal gland in Case 1 and the orbital masses on both sides in Case 2 showed infiltration of immunoglobulin-G4-positive plasma cells.
ISSN:1439-7595
1439-7609
DOI:10.3109/14397595.2016.1174421