Ageing and free-living daily physical activity effects on salivary beta-defensin 2 secretion

This study examined ageing and free-living daily physical activity effects on salivary human beta-defensin 2 (hBD2). A total of 168 healthy elderly and 26 healthy young volunteers underwent saliva sampling. Free-living step count, energy expenditure and activity durations at specific intensity level...

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Bibliographic Details
Published in:Journal of sports sciences 2017-04, Vol.35 (7), p.617-623
Main Authors: Shimizu, Kazuhiro, Hanaoka, Yukichi, Akama, Takao, Kono, Ichiro
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
ageing
Aging
Aging - immunology
Aging - metabolism
Antimicrobial agents
Antimicrobial peptide
beta-Defensins - secretion
defensin
Exercise
Exercise - physiology
Female
Humans
Male
Mouth - immunology
Mouth - metabolism
oral immune function
Peptides
physical activity
Physical Exertion - physiology
Reference Values
Respiratory Tract Infections - prevention & control
Saliva - metabolism
Young Adult
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Summary:This study examined ageing and free-living daily physical activity effects on salivary human beta-defensin 2 (hBD2). A total of 168 healthy elderly and 26 healthy young volunteers underwent saliva sampling. Free-living step count, energy expenditure and activity durations at specific intensity levels (inactive, light, moderate and vigorous) were evaluated. The results show significantly lower salivary hBD2 secretion rates for elderly than for young participants (P 
ISSN:0264-0414
1466-447X
DOI:10.1080/02640414.2016.1182640