Quantitative EEG Neurometric Analysis–Guided Neurofeedback Treatment in Postconcussion Syndrome (PCS): Forty Cases. How Is Neurometric Analysis Important for the Treatment of PCS and as a Biomarker?

• Published in: Clinical EEG and neuroscience 2017-05, Vol.48 (3), p.217-230
• Main Authors: Surmeli, Tanju, Eralp, Emin, Mustafazade, Ilham, Kos, Ismet Hadi, Özer, Gül Elif, Surmeli, Orkun H.
• Format: Article
• Language: English
• Subjects: Adult; Biomarkers - analysis; Brain - physiopathology; Electroencephalography - methods; Female; Head injuries; Humans; Magnetic Resonance Imaging - methods; Male; Neurofeedback - physiology; Neuropsychological Tests; Post-Concussion Syndrome - physiopathology; Psychiatric Status Rating Scales; Psychotropic drugs; Studies; Traumatic brain injury; Young Adult
• ISSN: 1550-0594; 2169-5202
• DOI: 10.1177/1550059416654849

Postconcussion syndrome (PCS) has been used to describe a range of residual symptoms that persist 12 months or more after the injury, often despite a lack of evidence of brain abnormalities on magnetic resonance imaging and computed tomography scans. In this clinical case series, the efficacy of quantitative EEG–guided neurofeedback in 40 subjects diagnosed with PCS was investigated. Overall improvement was seen in all the primary (Symptom Assessment-45 Questionnaire, Clinical Global Impressions Scale, Hamilton Depression Scale) and secondary measures (Minnesota Multiphasic Personality Inventory, Test of Variables for Attention). The Neuroguide Traumatic Brain Index for the group also showed a decrease. Thirty-nine subjects were followed up long term with an average follow-up length of 3.1 years (CI = 2.7-3.3). All but 2 subjects were stable and were off medication. Overall neurofeedback treatment was shown to be effective in this group of subjects studied.