Association of alcohol consumption with coronary artery disease severity

• Published in: Clinical nutrition (Edinburgh, Scotland) Scotland), 2017-08, Vol.36 (4), p.1036-1039
• Main Authors: Chagas, Patricia, Mazocco, Leticia, Piccoli, Jacqueline, Ardenghi, Thiago Machado, Badimon, Lina, Avancini Caramori, Paulo Ricardo, Pellanda, Lucia, Gomes, Irênio, Augustin Schwanke, Carla Helena
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Alcohol Abstinence; Alcohol consumption; Alcohol Drinking - adverse effects; Alcoholism - physiopathology; Brazil - epidemiology; Coronary Angiography; Coronary artery disease; Coronary Artery Disease - diagnostic imaging; Coronary Artery Disease - epidemiology; Coronary Artery Disease - etiology; Coronary Artery Disease - physiopathology; Coronary Vessels - diagnostic imaging; Cross-Sectional Studies; Female; Gastroenterology and Hepatology; Hospitals, Urban; Humans; Male; Middle Aged; Nutrition; Risk Factors; Self Report; Severity of Illness Index; Young Adult
• ISSN: 0261-5614; 1532-1983
• DOI: 10.1016/j.clnu.2016.06.017

Summary Background & Aims The ingestion of small to moderate alcohol consumption amounts has been associated to cardiovascular protection. This study aimed to evaluate the association between alcohol consumption and coronary artery disease severity. Material and Methods Cross-sectional Study with patients undergoing coronary angiography. Age, cardiovascular risk factors (smoking, systemic arterial hypertension, dyslipidemia and diabetes) and alcohol drinking habit were investigated. Alcohol consumption was divided in three categories: nondrinker, moderate alcohol consumption (less than 15g ethanol/day for women or 30g ethanol/day for men) and heavy alcohol consumption. Coronary artery disease severity was assessed through the Friesinger Score (FS) in the coronary angiography, by interventional cardiologists blinded to alcohol consumption. Results The final sample included 363 adults; of those, 228 were men (62.81%). Mean age was 60.5±10.9y. Unadjusted analyses identified sex, age, hypertension, diabetes, dyslipidemia and alcohol consumption as the main covariates associated with the Friesinger score. Lower Friesinger scores were also observed in moderate alcohol consumption when comparing to those who do not drink (RR 0.86; 95%CI 0.79-0.95). Conclusion Among patients with suspected coronary artery disease undergoing coronary angiography, moderate alcohol consumption is associated to a lower coronary artery disease severity than heavy drinking.