Depressive Symptoms: Mediator of Event-Free Survival in Patients With Heart Failure

Depressive symptoms and poor health perceptions are predictors of higher hospitalization and mortality rates (heart failure [HF]). However, the association between depressive symptoms and health perceptions as they affect event-free survival outcomes in patients with HF has not been studied. The pur...

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Bibliographic Details
Published in:Western journal of nursing research 2017-04, Vol.39 (4), p.539-552
Main Authors: Hammash, Muna H., Lennie, Terry A., Crawford, Timothy, Heo, Seongkum, Chung, Misook L., Biddle, Martha J., Dekker, Rebecca, Wu, Jia-Rong, Rayens, Mary Kay, Moser, Debra K.
Format: Article
Language:English
Subjects:
Clinical outcomes
Depression - psychology
Disease-Free Survival
Female
Health psychology
Health risk assessment
Health Status
Heart failure
Heart Failure - psychology
Heart surgery
Hospitalization
Humans
Male
Mental depression
Middle Aged
Mortality rates
Nursing
Perceptions
Prospective Studies
Quantitative analysis
Questionnaires
Surveys and Questionnaires
Symptoms
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Summary:Depressive symptoms and poor health perceptions are predictors of higher hospitalization and mortality rates (heart failure [HF]). However, the association between depressive symptoms and health perceptions as they affect event-free survival outcomes in patients with HF has not been studied. The purpose of this secondary analysis was to determine whether depressive symptoms mediate the relationship between health perceptions and event-free survival in patients with HF. A total of 458 HF patients (61.6 ± 12 years, 55% New York Heart Association Class III/IV) responded to one-item health perception question and completed the Patient Health Questionnaire–9. Event-free survival data were collected for up to 4 years. Multiple regression and Cox proportional hazards regression analysis showed that depressive symptoms mediated the relationship between health perceptions and event-free survival. Decreasing depressive symptoms is essential to improve event-free survival in patients with HF.
ISSN:0193-9459
1552-8456
DOI:10.1177/0193945916658883