Influences of non-canonical neurosteroid signaling on developing neural circuits

Highlights • There is growing appreciation for flexible mechanisms to influence development of neural circuits. • Neurosteroids can be modulated by the environment and provisioned specially to neural circuits. • Recent studies demonstrate how neurosteroids influence neurites and synaptic function, k...

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Bibliographic Details
Published in:Current opinion in neurobiology 2016-10, Vol.40, p.103-110
Main Author: London, Sarah E
Format: Article
Language:English
Subjects:
Animals
Brain - embryology
Brain - growth & development
Humans
Neurology
Neurotransmitter Agents - physiology
Psychiatry
Signal Transduction - physiology
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Summary:Highlights • There is growing appreciation for flexible mechanisms to influence development of neural circuits. • Neurosteroids can be modulated by the environment and provisioned specially to neural circuits. • Recent studies demonstrate how neurosteroids influence neurites and synaptic function, key factors in circuit organization. • The diversity of neurosteroids suggests high potential for nuanced modulation of many developmental processes.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2016.06.018