The changes of individual carotid artery wall layer by aging and carotid intima‐media thickness value for high risk

• Published in: Cardiovascular therapeutics 2016-12, Vol.34 (6), p.397-403
• Main Authors: Bae, Jang‐Ho, Kim, Wuon‐Shik, Lee, Moo‐Sik, Kim, Kee‐Sik, Park, Jeong Bae, Youn, Ho‐Joong, Park, Chang‐Gyu, Hong, Kyung‐Soon, Kim, Jang‐Young, Jeong, Jin‐Won, Park, Jong Chun, Lim, Do‐Sun, Kim, Moo Hyun, Woo, Jeong Taek
• Format: Article
• Language: English
• Subjects: Adult; Age Factors; Aged; Aging; Arterial intima; Arterial media; Asymptomatic Diseases; Carotid artery; Carotid Artery Diseases - diagnostic imaging; Carotid Artery, Common - diagnostic imaging; Carotid Intima-Media Thickness; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Republic of Korea; Risk Assessment; Risk Factors; Software; Time Factors
• ISSN: 1755-5914; 1755-5922
• DOI: 10.1111/1755-5922.12209

Summary Aim It is still unclear which layer (intima or media) is mainly involved in increased carotid intima‐media thickness (CIMT) by aging and also unclear regarding CIMT value suggesting high cardiovascular risk, although 75th percentile value of CIMT is known as a high risk in asymptomatic adults. We sought to find the changes of carotid intima thickness (CIT) and carotid media thickness (CMT) by aging and the 75th percentile value of CIMT in asymptomatic Korean adults. Method This is an observational cohort study. Carotid ultrasound findings (n=2204 from 12 hospitals) were prospectively collected. The carotid images were sent to Korea Research Institute of Standards and Science for analysis using specialized software which can measure intima and media wall also. Results Mean age was 58.1±13.5 years old (52% of men). Pearson's correlation coefficient between age and right CIMT (r=.489, P