Spanish Validation of the Problem Behaviors Assessment–Short (PBA-s) for Huntington’s Disease

A prospective, observational multicenter study was carried out assessing neuropsychiatric symptoms in a sample of 117 subjects in order to validate the Spanish version of the Problem Behaviors Assessment-Short (PBA-s). The psychometric properties of this version were analyzed. Inter- and intra-rater...

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Published in:The journal of neuropsychiatry and clinical neurosciences 2017, Vol.29 (1), p.31-38
Main Authors: Ruiz-Idiago, Jesús M, Floriach, Misericordia, Mareca, Cèlia, Salvador, Raymond, López-Sendón, José Luis, Mañanés, Verónica, Cubo, Esther, Mariscal, Natividad, Muñoz, Esteban, Santacruz, Pilar, Noguera, María F, Vivancos, Laura, Roy, Pedro, Pomarol-Clotet, Edith, Sarró, Salvador
Format: Article
Language:English
Subjects:
Adult
Factor Analysis, Statistical
Female
Humans
Huntington Disease - diagnosis
Huntington Disease - drug therapy
Huntington Disease - genetics
Huntington Disease - psychology
Interview, Psychological
Male
Middle Aged
Neuropsychological Tests
Observer Variation
Problem Behavior
Prospective Studies
Psychiatric Status Rating Scales
Psychometrics
Translating
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Summary:A prospective, observational multicenter study was carried out assessing neuropsychiatric symptoms in a sample of 117 subjects in order to validate the Spanish version of the Problem Behaviors Assessment-Short (PBA-s). The psychometric properties of this version were analyzed. Inter- and intra-rater reliability were good: the mean weighted Cohen’s kappa was 0.90 for severity scores and 0.93 for frequency scores. Four factors accounting for 56% of the total variance were identified after an exploratory factor analysis: apathy, irritability, depression, and perseveration. The PBA-s correlates strongly with the Neuropsychiatric Inventory, demonstrating its accuracy for assessing neuropsychiatric symptoms in patients with Huntington’s disease.
ISSN:0895-0172
1545-7222
DOI:10.1176/appi.neuropsych.16020025