One-Hour Postload Hyperglycemia Confers Higher Risk of Hepatic Steatosis to HbA1c-Defined Prediabetic Subjects
Context: Individuals with glycated hemoglobin (HbA1c)-defined prediabetes (HbA1c value of 5.7–6.4%) and 1-hour plasma glucose ≥155 mg/dL during an oral glucose tolerance test have an increased risk of developing type 2 diabetes. Objective: To evaluate the degree to which HbA1c-defined prediabetes an...
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Published in: | The journal of clinical endocrinology and metabolism 2016-11, Vol.101 (11), p.4030-4038 |
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Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
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Summary: | Context:
Individuals with glycated hemoglobin (HbA1c)-defined prediabetes (HbA1c value of 5.7–6.4%) and 1-hour plasma glucose ≥155 mg/dL during an oral glucose tolerance test have an increased risk of developing type 2 diabetes.
Objective:
To evaluate the degree to which HbA1c-defined prediabetes and 1-hour postload glucose ≥155 mg/dL individually and jointly associate with hepatic steatosis and related biomarkers.
Design and Patients:
A cross-sectional analysis was performed on 1108 White individuals.
Setting:
Ambulatory care.
Main Outcome Measures:
Anthropometric and metabolic characteristics including hepatic steatosis assessed by ultrasonography.
Results:
Compared with the normal group (HbA1c |
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ISSN: | 0021-972X 1945-7197 |
DOI: | 10.1210/jc.2016-1856 |