Association of metabolic syndrome and 25‐hydroxyvitamin D with cognitive impairment among elderly Koreans

• Published in: Geriatrics & gerontology international 2017-07, Vol.17 (7), p.1069-1075
• Main Authors: Lee, Eun Young, Lee, Su Jin, Kim, Kyoung Min, Yun, Young Mi, Song, Bo Mi, Kim, Jong Eun, Kim, Hyeon Chang, Rhee, Yumie, Youm, Yoosik, Kim, Chang Oh
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Analysis of Variance; Cognitive Dysfunction - diagnosis; Cognitive Dysfunction - epidemiology; cognitive impairment; Cohort Studies; Comorbidity; elderly; Female; Geriatric Assessment; Humans; Independent Living; Korea - epidemiology; Logistic Models; Male; metabolic syndrome; Metabolic Syndrome - diagnosis; Metabolic Syndrome - epidemiology; Odds Ratio; Prevalence; Prognosis; Prospective Studies; Risk Assessment; Rural Population; Severity of Illness Index; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D Deficiency - diagnosis; Vitamin D Deficiency - epidemiology; vitamin D
• ISSN: 1444-1586; 1447-0594
• DOI: 10.1111/ggi.12826

Aim Metabolic syndrome and vitamin D deficiency are prevalent in older adults, and are considered risk factors for cognitive impairment. We investigated the combined effects of MetS and serum 25‐hydroxyvitamin D (25[OH]D) levels on cognitive function in older adults. Methods We studied 2940 participants aged ≥65 years from the Korean Urban Rural Elderly cohort study. Metabolic syndrome was defined according to the updated Adult Treatment Panel III criteria. Serum 25(OH)D levels were categorized into four groups: