Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes

This study identified polymorphisms in the DGAT1 gene in Murrah buffaloes and investigated the associations to milk production and quality traits (milk, fat and protein yields and percentages, somatic cell count). Genomic DNA was extracted from hair follicles collected from the tail of 196 females....

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Bibliographic Details
Published in:Tropical animal health and production 2016-10, Vol.48 (7), p.1421-1426
Main Authors: de Freitas, Ana Cláudia, de Camargo, Gregório Miguel Ferreira, Stafuzza, Nedenia Bonvino, Aspilcueta-Borquis, Rusbel Raul, Venturini, Guilherme Costa, Dias, Marina Mortati, Cardoso, Diercles Francisco, Tonhati, Humberto
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Brazil
Buffaloes - genetics
Buffaloes - physiology
Dairying
Diacylglycerol O-Acyltransferase - genetics
Female
Genotype
Lactation - genetics
Lactation - physiology
Life Sciences
Milk - secretion
Milk production
Phenotype
Polymorphism, Single Nucleotide
Regular Articles
Statistical analysis
Tropical Climate
Veterinary Medicine/Veterinary Science
Zoology
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Summary:This study identified polymorphisms in the DGAT1 gene in Murrah buffaloes and investigated the associations to milk production and quality traits (milk, fat and protein yields and percentages, somatic cell count). Genomic DNA was extracted from hair follicles collected from the tail of 196 females. Three SNPs were identified in DGAT1 gene by sequencing. Statistical analyses were performed to verify the linkage and the association between polymorphisms and traits. The estimated value of r 2 between two SNPs in exon 17 (g.11,783G > A and g.11,785 T > C) was 0.029. SNP g.11,785 T > C was significantly associated ( P  
ISSN:0049-4747
1573-7438
DOI:10.1007/s11250-016-1110-x