Chemerin and interleukin-6 levels in obese individuals following periodontal treatment

Objective To investigate changes in the levels of gingival crevicular fluid (GCF) chemerin and interleukin‐6 (IL‐6) in both obese/non‐obese individuals with periodontitis following non‐surgical periodontal therapy. Methods Individuals (n = 80) were split into four groupings according to periodontal/...

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Bibliographic Details
Published in:Oral diseases 2016-10, Vol.22 (7), p.673-680
Main Authors: Balli, U, Ongoz Dede, F, Bozkurt Dogan, S, Gulsoy, Z, Sertoglu, E
Format: Article
Language:English
Subjects:
Adult
chemerin protein
Chemokines - analysis
Dentistry
Female
gingival crevicular fluid
Glycoproteins
Gum disease
human
Humans
Intercellular Signaling Peptides and Proteins - analysis
interleukin-6
Interleukin-6 - analysis
Leukocytes
Male
Obesity
Obesity - metabolism
periodontal disease
Periodontal Diseases - therapy
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Summary:Objective To investigate changes in the levels of gingival crevicular fluid (GCF) chemerin and interleukin‐6 (IL‐6) in both obese/non‐obese individuals with periodontitis following non‐surgical periodontal therapy. Methods Individuals (n = 80) were split into four groupings according to periodontal/anthropometric parameters: (i) periodontal healthy without obesity; (ii) chronic periodontitis (CP) without obesity; (iii) periodontal healthy with obesity; and (iv) CP with obesity. Individuals with periodontitis were treated with non‐surgical periodontal therapy. Both GCF sampling procedures and clinical periodontal measures were performed prior to treatment and 6 weeks thereafter. Enzyme‐linked immunosorbent assay was utilized to measure both chemerin and IL‐6 levels. Results Greater values for chemerin and IL‐6 were observed in obese individuals compared to their non‐obese controls and in individuals with CP compared to their periodontal healthy controls (P 
ISSN:1354-523X
1601-0825
DOI:10.1111/odi.12520