Expression of Cytokine Genes and Growth Factors in Rat Lungs and Kidneys after Subtotal Hepatectomy

Expression of il1b, il6, il10, tnfa, hgf, tgfb, vegf, and fgf2 genes in the lungs and kidneys was examined on rat model of liver regeneration after subtotal hepatectomy. Enhanced expression of il6, il10, tnfa, hgf, and fgf2 genes was detected at the early terms after 80% liver resection.

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2016-07, Vol.161 (3), p.395-399
Main Authors: Elchaninov, A. V., Fatkhudinov, T. Kh, Usman, N. Yu, Arutyunyan, I. V., Makarov, A. V., Kananykhina, E. Yu, Glinkina, V. V., Bolshakova, G. B., Sukhikh, G. T.
Format: Article
Language:English
Subjects:
Animals
Biomedical and Life Sciences
Biomedicine
Cell Biology
Cytokines
Endothelial growth factors
Fibroblast growth factors
Gene expression
Genes
Glucagon
Hepatectomy
Hepatocyte Growth Factor - metabolism
Interleukin-10 - metabolism
Interleukin-6 - metabolism
Internal Medicine
Kidney - metabolism
Laboratory Medicine
Liver Regeneration - physiology
Lung - metabolism
Pathology
Rats
Rats, Sprague-Dawley
Transforming Growth Factor beta - metabolism
Tumor Necrosis Factor-alpha - metabolism
Vascular Endothelial Growth Factor A - metabolism
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Summary:Expression of il1b, il6, il10, tnfa, hgf, tgfb, vegf, and fgf2 genes in the lungs and kidneys was examined on rat model of liver regeneration after subtotal hepatectomy. Enhanced expression of il6, il10, tnfa, hgf, and fgf2 genes was detected at the early terms after 80% liver resection.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-016-3423-1