Medical Comorbidity of Attention-Deficit/Hyperactivity Disorder in US Adolescents

Understanding patterns of medical comorbidity in attention-deficit/hyperactivity disorder (ADHD) may lead to better treatment of affected individuals as well as aid in etiologic study of disease. This article provides the first systematic evaluation on the medical comorbidity of ADHD in a nationally...

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Bibliographic Details
Published in:Journal of child neurology 2016-10, Vol.31 (11), p.1282-1289
Main Authors: Jameson, Nicole D., Sheppard, Brooke K., Lateef, Tarannum M., Vande Voort, Jennifer L., He, Jian-Ping, Merikangas, Kathleen Ries
Format: Article
Language:English
Subjects:
Adolescent
Attention Deficit Disorder with Hyperactivity - complications
Attention Deficit Disorder with Hyperactivity - epidemiology
Comorbidity
Cross-Sectional Studies
Female
Humans
Male
Odds Ratio
Prevalence
Surveys and Questionnaires
United States - epidemiology
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Summary:Understanding patterns of medical comorbidity in attention-deficit/hyperactivity disorder (ADHD) may lead to better treatment of affected individuals as well as aid in etiologic study of disease. This article provides the first systematic evaluation on the medical comorbidity of ADHD in a nationally representative sample (National Comorbidity Replication Survey–Adolescent Supplement; N = 6483) using formal diagnostic criteria. Survey-weighted odds ratios adjusted for demographics, additional medical, and mental disorders were calculated for associations between ADHD and medical conditions. Models adjusted for demographics revealed significantly increased odds of allergy, asthma, enuresis, headache/migraine, and serious stomach or bowel problems. After adjusting for comorbidity, across the medical conditions, enuresis and serious stomach problems were the strongest correlates of ADHD. These findings confirm the pervasive medical comorbidity of ADHD reported in previous clinical and community-based studies. The intriguing salience of enuresis and serious stomach or bowel conditions may also provide an important clue to multisystem involvement in ADHD.
ISSN:0883-0738
1708-8283
DOI:10.1177/0883073816653782