Usefulness of the monocyte-to-high-density lipoprotein cholesterol ratio to predict bare metal stent restenosis

The aim of the present study was to investigate the predictive value of preprocedural monocyte count-to-high-density lipoprotein cholesterol ratio (MHR) on development of in-stent restenosis in patients undergoing coronary bare-metal stent (BMS) implantation. Data from 705 patients who had undergone...

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Bibliographic Details
Published in:Biomarkers in medicine 2016-09, Vol.10 (9), p.959-966
Main Authors: Yilmaz, Samet, Akboga, Mehmet K, Sen, Fatih, Balc, Kevser G, Aras, Dursun, Temizhan, Ahmet, Aydogdu, Sinan
Format: Article
Language:English
Subjects:
Aged
Angina pectoris
Angiography
Area Under Curve
Biomarkers
Blood
C-reactive protein
C-Reactive Protein - analysis
Cardiology
Cell adhesion & migration
Cholesterol
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Coronary Angiography
Coronary Restenosis - diagnosis
Coronary Restenosis - pathology
Coronary Restenosis - therapy
Coronary vessels
Diabetes
Diabetes mellitus
Female
Heart attacks
high-density lipoprotein cholesterol
Humans
Implants
Inflammation
Lipoproteins
Logistic Models
Male
Medical imaging
Middle Aged
monocyte count
Monocytes
Monocytes - cytology
Neutrophils
Odds Ratio
Patients
Predictive Value of Tests
Regression analysis
Restenosis
ROC Curve
Smoking
stent restenosis
Stents
Thrombosis
Veins & arteries
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Summary:The aim of the present study was to investigate the predictive value of preprocedural monocyte count-to-high-density lipoprotein cholesterol ratio (MHR) on development of in-stent restenosis in patients undergoing coronary bare-metal stent (BMS) implantation. Data from 705 patients who had undergone BMS implantation and additional control coronary angiography were analyzed. Patients were divided into three tertiles based on preprocedural MHR. Restenosis occurred in 59 patients (25%) in the lowest tertile, 84 (35%) in the middle tertile and 117 (50%) in the highest MHR tertile (p < 0.001). Using multiple logistic regression analysis, smoking, diabetes mellitus, stent length, preprocedural MHR and C-reactive protein levels emerged as independent predictors of in-stent restenosis. High preprocedural MHR is related to BMS restenosis.
ISSN:1752-0363
1752-0371
DOI:10.2217/bmm-2016-0069