Resting-state functional MR imaging shed insights into the brain of diabetes

Diabetes mellitus is a common metabolic disease which is associated with increasing risk for multiple cognitive declines. Alterations in brain functional connectivity are believed to be the mechanisms underlying the cognitive function impairments. During the past decade, resting-state functional mag...

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Bibliographic Details
Published in:Metabolic brain disease 2016-10, Vol.31 (5), p.993-1002
Main Authors: Wang, Yun Fei, Ji, Xue Man, Lu, Guang Ming, Zhang, Long Jiang
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Biomedicine
Brain - diagnostic imaging
Brain - metabolism
Diabetes Mellitus - diagnostic imaging
Diabetes Mellitus - metabolism
Diabetic Neuropathies - diagnostic imaging
Diabetic Neuropathies - metabolism
Humans
Magnetic Resonance Imaging - methods
Metabolic Diseases
Neurology
Neurosciences
Oncology
Rest - physiology
Review Article
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Summary:Diabetes mellitus is a common metabolic disease which is associated with increasing risk for multiple cognitive declines. Alterations in brain functional connectivity are believed to be the mechanisms underlying the cognitive function impairments. During the past decade, resting-state functional magnetic resonance imaging (rs-fMRI) has been developed as a major tool to study brain functional connectivity in vivo. This paper briefly reviews the diabetes-associated cognitive impairment, analysis algorithms and clinical applications of rs-fMRI. We also provide future perspectives of rs-fMRI in diabetes.
ISSN:0885-7490
1573-7365
DOI:10.1007/s11011-016-9872-4