Alcohol intake and bone metabolism in elderly women

Published reports on the effect of alcohol consumption on bone mineral density (BMD) are inconsistent. The objective of this study was to examine the relation between alcohol intake and BMD, calcitropic hormones, calcium absorption, and other biochemical indexes of bone and mineral metabolism in eld...

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Bibliographic Details
Published in:The American journal of clinical nutrition 2000-11, Vol.72 (5), p.1206-1213
Main Authors: RAPURI, Prema B, GALLAGHER, J. Christopher, BALHORN, Kurt E, RYSCHON, Kay L
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Absorption
Aged
Alcohol Drinking
Alcohol use
Biological and medical sciences
Biomarkers - blood
Biomarkers - urine
Bone and Bones - metabolism
Bone Density
Bone Remodeling
Bones
Calcifediol - blood
Calcitriol - blood
Calcium - metabolism
Collagen - urine
Collagen Type I
Ethanol - adverse effects
Female
Fundamental and applied biological sciences. Psychology
Hormones
Humans
Metabolism
Older people
Osteocalcin - blood
Parathyroid Hormone - blood
Peptides - urine
Radius
Skeleton and joints
Spine
Vertebrates: osteoarticular system, musculoskeletal system
Women
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Summary:Published reports on the effect of alcohol consumption on bone mineral density (BMD) are inconsistent. The objective of this study was to examine the relation between alcohol intake and BMD, calcitropic hormones, calcium absorption, and other biochemical indexes of bone and mineral metabolism in elderly women. The results presented are derived from baseline observations of 489 elderly women (aged 65-77 y) recruited for an osteoporosis study. The nondrinking group comprised 297 women and the drinking group comprised 148 women. Furthermore, the effect of different alcohol intakes (28.6 to 57.2 to 142.9 g/wk) was studied. Women who consumed alcohol had significantly higher spine (10%), total body (4.5%), and midradius (6%) BMD than did nondrinkers. An alcohol intake >28.6 g/wk was associated with higher BMD; maximum effect was seen with an intake of >28.6 to
ISSN:0002-9165
1938-3207
DOI:10.1093/ajcn/72.5.1206