Endocrine disruption caused by two common pollutants at “acceptable” concentrations

This report focuses on the impact of low concentrations of two purported endocrine-disrupting xenobiotic compounds, nonylphenol and methoxychlor, on two freshwater teleosts of the genus Xiphophorus, X. maculatus, commonly known as the platyfish, and X. helleri, commonly known as the swordtail. Nonyl...

Full description

Saved in:
Bibliographic Details
Published in:Neurotoxicology and teratology 2002, Vol.24 (1), p.71-79
Main Authors: Magliulo, Lucia, Schreibman, Martin P, Cepriano, Jessica, Ling, Jacquline
Format: Article
Language:English
Subjects:
Animals
Cyprinodontiformes - growth & development
Endocrine disrupter
Endocrine Glands - drug effects
Endocrine Glands - pathology
Female
Insecticides - toxicity
Male
Methoxychlor
Methoxychlor - toxicity
Nonylphenol
Phenols - toxicity
Platyfish
Reproduction
Reproduction - drug effects
Sexual Maturation - drug effects
Swordtail
Water Pollutants, Chemical - toxicity
Xiphophorus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This report focuses on the impact of low concentrations of two purported endocrine-disrupting xenobiotic compounds, nonylphenol and methoxychlor, on two freshwater teleosts of the genus Xiphophorus, X. maculatus, commonly known as the platyfish, and X. helleri, commonly known as the swordtail. Nonylphenol exposure increased mortality rates, elicited stress behaviors, decreased body weight and significantly hampered gonadal development and reproductive function. Methoxychlor exposure elicited stress behaviors, decreased body weight and significantly retarded sexual development. This report demonstrates that, even at “acceptable” concentrations, these compounds pose a serious threat to our aquatic ecosystems.
ISSN:0892-0362
1872-9738
DOI:10.1016/S0892-0362(01)00190-8