Detection of genes with deleterious alleles in an inbred line of tilapia ( Oreochromis aureus)

An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny...

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Bibliographic Details
Published in:Aquaculture 2002-04, Vol.206 (3), p.151-164
Main Authors: Palti, Y, Shirak, A, Cnaani, A, Hulata, G, Avtalion, R.R, Ron, M
Format: Article
Language:English
Subjects:
Animal aquaculture
Animal productions
Animals
Aquaculture
Biological and medical sciences
Classical genetics, quantitative genetics, hybrids
Deleterious genes
DNA markers
fish culture
Freshwater
Fundamental and applied biological sciences. Psychology
Genes
Genetics of eukaryotes. Biological and molecular evolution
Genomics
Gynogenesis
Oreochromis aureus
Pisciculture
Tilapia
Vertebrata
Vertebrate aquaculture
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Summary:An increase in the viability of gynogenetic progeny has been recorded in Bar Ilan University (BIU) by following four successive generations of meiogynogenetic Oreochromis aureus. This augmentation is suggested to be the result of reduction in the number of deleterious alleles. The genome of progeny of the fourth successive generation of meiogynogenetic O. aureus was screened with 76 microsatellite DNA markers to identify polymorphic loci. Twenty polymorphic markers were tested for segregation distortion in four crosses of informative progeny to identify linkage to genes with recessive deleterious alleles. Significant distortion ( P
ISSN:0044-8486
1873-5622
DOI:10.1016/S0044-8486(01)00727-X