Growth and micronutrient disturbances in stable, HIV-infected children in Cape Town

This prospective study of 60 stable, HIV-infected children in an economically deprived setting was designed to document anthropometric and micronutrient disturbances. Investigations included CD4+ counts, anthropometry and plasma levels of albumin, transthyretin, retinol-binding protein (RBP), vitami...

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Bibliographic Details
Published in:Annals of tropical paediatrics 2002-03, Vol.22 (1), p.19-23
Main Authors: Eley, Brian S., Sive, Alan A., Abelse, Lisa, Kossew, Glynis, Cooper, Margaret, Hussey, Gregory D.
Format: Article
Language:English
Subjects:
Anthropometry
Biological and medical sciences
C-Reactive Protein - analysis
CD4 antigen
CD4 Lymphocyte Count
Child, Preschool
Female
Growth Disorders - blood
Growth Disorders - complications
HIV Infections - blood
HIV Infections - complications
HIV Infections - immunology
Human immunodeficiency virus
Human viral diseases
Humans
Immune Tolerance
Infant
Infectious diseases
Male
Medical sciences
Micronutrients - blood
Poverty
Prospective Studies
retinol-binding protein
South Africa
transthyretin
Tropical medicine
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Vitamin B12
Vitamin B6
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Summary:This prospective study of 60 stable, HIV-infected children in an economically deprived setting was designed to document anthropometric and micronutrient disturbances. Investigations included CD4+ counts, anthropometry and plasma levels of albumin, transthyretin, retinol-binding protein (RBP), vitamins A, B 6 , E and B 12 , and folate, zinc and copper. The median age was 25 months. Thirty-two per cent had mild, 48% moderate and 20% severe clinical features, and 80% were moderately or severely immunosuppressed. Twenty-eight per cent had a weight Z-score
ISSN:0272-4936
1465-3281
DOI:10.1179/027249302125000111