Effects of 12‐week resistance training during radiotherapy in breast cancer patients

• Published in: Scandinavian journal of medicine & science in sports 2017-11, Vol.27 (11), p.1500-1510
• Main Authors: Wiskemann, J., Schmidt, M. E., Klassen, O., Debus, J., Ulrich, C. M., Potthoff, K., Steindorf, K.
• Format: Article
• Language: English
• Subjects: Adult; Breast cancer; Breast Neoplasms - radiotherapy; Chemotherapy; Exercise; Exercise Therapy; Fatigue - therapy; Female; fitness; Humans; isokinetic; Isometric Contraction; Knee; Knee Joint - physiology; Middle Aged; Muscle Strength; oncology; Physical activity; Prospective Studies; Radiation therapy; Range of Motion, Articular; Resistance Training; Shoulder Joint - physiology; Sports training; strength; Strength training; Torque
• ISSN: 0905-7188; 1600-0838
• DOI: 10.1111/sms.12777

Exercise is considered to be an effective supportive treatment approach in breast cancer (BC) patients. We conducted a randomized controlled trial to assess the efficacy of a 12‐week PRT during radiotherapy. Strength performance was assessed by maximal isokinetic peak torque (MIPT) in two different angular velocities (60°/s and 180°/s) and maximal voluntary isometric contraction for shoulder external and internal rotation, as well as for knee extension and flexion were assessed pre‐ and post‐intervention in 146 patients randomized to PRT or a control group. Statistical analyses were based on analysis of covariance models for the individual changes from baseline to week 13. Intention‐to‐treat analyses showed significant between‐group differences favoring the exercise group (EX) for MIPT in knee flexion and shoulder internal and external rotation (P