Isolating tape method is useful for an early judgment of curability during pancreaticoduodenectomy for pancreatic cancer

• Published in: Journal of hepato-biliary-pancreatic sciences 2016-10, Vol.23 (10), p.E20-E24
• Main Authors: Fujioka, Shuichi, Misawa, Takeyuki, Yanaga, Katsuhiko
• Format: Article
• Language: English
• Subjects: Aged; Ampulla of Vater - pathology; Ampulla of Vater - surgery; Brachial Plexus; Clinical Decision-Making; Cohort Studies; Curative resection; Extrapancreatic nerve plexus; Female; Follow-Up Studies; Humans; Intraoperative Care - methods; Male; Margins of Excision; Middle Aged; Pancreas - innervation; Pancreas - surgery; Pancreatic cancer; Pancreatic Neoplasms; Pancreatic Neoplasms - mortality; Pancreatic Neoplasms - parasitology; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Pancreaticoduodenectomy; Pancreaticoduodenectomy - methods; Pancreaticoduodenectomy - mortality; Periampullary carcinoma; Pilot Projects; Prognosis; Surgical Tape; Survival Rate; Treatment Outcome
• ISSN: 1868-6974; 1868-6982
• DOI: 10.1002/jhbp.381

Positive surgical margin of extrapancreatic nerve plexus (ENP) is a major cause of non‐curative resection during pancreaticoduodenectomy (PD) for periampullary carcinoma (PC), which is difficult to detect at the early stage of PD. We describe a novel surgical technique using an isolating tape (iTape)‐oriented ENP‐first dissection (IOEFD) during PD. The iTape is firstly passed through the retroperitoneal space between ENP and inferior vena cava. Then, the iTape is further extracted from major vessels such as the common hepatic and superior mesenteric artery. Consequently, the iTape encircles ENP alone. By tugging both ends of the iTape and vessel tapes to various directions from the caudal and cranial side of the pancreas, ENP is individually dissected without dividing any organ or tissue. Ten patients with periampullary carcinomas, consisting of one distal bile duct carcinoma, four ampullary carcinomas and five pancreatic head carcinomas underwent IOEFD during PD. Among these, nine underwent PDs after confirming negative surgical margin of ENP by IOEFD, while in the other case, PD was abandoned and converted to digestive bypass because of positive ENP margin during IOEFD. By final pathological diagnosis, R0 resection has been established in all nine patients who underwent PD with IOEFDs. Our pilot study indicated that inappropriate non‐curative resection can be avoided by IOEFD during PD. Highlight Fujioka and colleagues report on their procedure of nerve plexus‐first dissection using an isolating tape for early judgment of curability and resectability during pancreaticoduodenectomy for pancreatic cancer. This technique is characterized by the isolation and anterior dissection of the nerve plexus without dividing any organs in the secured surgical field.