Feelings of shame, embarrassment and guilt and their neural correlates: A systematic review

• Published in: Neuroscience and biobehavioral reviews 2016-12, Vol.71, p.455-471
• Main Authors: Bastin, Coralie, Harrison, Ben J., Davey, Christopher G., Moll, Jorge, Whittle, Sarah
• Format: Article
• Language: English
• Subjects: Anger; Embarrassment; fMRI; Guilt; Humans; Magnetic Resonance Imaging; Morals; MRI; Negative moral emotions; Neuroimaging; PET; Shame
• ISSN: 0149-7634; 1873-7528
• DOI: 10.1016/j.neubiorev.2016.09.019

•We reviewed the literature on the neural correlates of shame, embarrassment and guilt.•Research points to both common and unique neural underpinnings of these emotions.•All three emotions appear to be associated with anterior insula activity.•Varying methodologies to induce emotion prevent strong conclusions to be made. This systematic review aimed to provide a comprehensive summary of the current literature on the neurobiological underpinnings of the experience of the negative moral emotions: shame, embarrassment and guilt. PsycINFO, PubMed and MEDLINE were used to identify existing studies. Twenty-one functional and structural magnetic resonance imaging and positron emission tomography studies were reviewed. Although studies differed considerably in methodology, their findings highlight both shared and distinct patterns of brain structure/function associated with these emotions. Shame was more likely to be associated with activity in the dorsolateral prefrontal cortex, posterior cingulate cortex and sensorimotor cortex; embarrassment was more likely to be associated with activity in the ventrolateral prefrontal cortex and amygdala; guilt was more likely to be associated with activity in ventral anterior cingulate cortex, posterior temporal regions and the precuneus. Although results point to some common and some distinct neural underpinnings of these emotions, further research is required to replicate findings.