Loading…
Amniotic fluid discordance in monochorionic diamniotic twin pregnancies is associated with increased risk for twin anemia-polycythemia sequence
Objective To estimate the risk for twin anemia–polycythemia sequence (TAPS) and adverse perinatal outcome in monochorionic diamniotic (MCDA) twin pregnancies with amniotic fluid discordance (AFD). Methods Retrospective cohort study of 34 MCDA pregnancies with AFD (intertwin difference of ≥3 cm in ma...
Saved in:
| Published in: | Prenatal diagnosis 2016-12, Vol.36 (12), p.1099-1103 |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c3519-8c5047448e040fa557e396463188bac6bb17f60204c2eb95a4bb23fbac6e59eb3 |
|---|---|
| cites | |
| container_end_page | 1103 |
| container_issue | 12 |
| container_start_page | 1099 |
| container_title | Prenatal diagnosis |
| container_volume | 36 |
| creator | Hiersch, Liran Eitan, Mayan Ashwal, Eran Weisz, Boaz Chayen, Benny Lipitz, Shlomo Yinon, Yoav |
| description | Objective
To estimate the risk for twin anemia–polycythemia sequence (TAPS) and adverse perinatal outcome in monochorionic diamniotic (MCDA) twin pregnancies with amniotic fluid discordance (AFD).
Methods
Retrospective cohort study of 34 MCDA pregnancies with AFD (intertwin difference of ≥3 cm in maximal vertical pocket measurement) without meeting the criteria for twin to twin transfusion syndrome or selective intrauterine growth restriction. Perinatal outcome measures and the risk for TAPS were compared with a control group consisted of 101 MCDA twin pregnancies without AFD, twin to twin transfusion syndrome, or selective intrauterine growth restriction. Composite neonatal morbidity was defined as the presence of respiratory distress syndrome, intraventricular hemorrhage grades 3 and 4, necrotizing enterocolitis or sepsis.
Results
Overall, in the AFD group, seven twin pairs (20.6%) were complicated by TAPS compared with none in the controls (p |
| doi_str_mv | 10.1002/pd.4939 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1835399115</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4275237131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3519-8c5047448e040fa557e396463188bac6bb17f60204c2eb95a4bb23fbac6e59eb3</originalsourceid><addsrcrecordid>eNpd0c1u1DAQAGALgehSEG-ALHFBQil2bMfxsSq0IK2AQwGJi-U4E9ZtEgc70bJPwSsz0bY9cBqP5hv_DSEvOTvjjJXvpvZMGmEekQ1nRhesLMVjsmEc16JW_IQ8y_kGYV0a_ZSclFoLqZjakL_nwxjiHDzt-iW0tA3Zx9S60QMNIx3iGP0uphBHJG1w93reY3VK8GtEGiDTkKnLOfrgZmjpPsw77PcJXMY0hXxLu5iObW6EIbhiiv3BH-bdmtAMvxfAQ5-TJ53rM7y4i6fk2-WH64uPxfbL1aeL823hheKmqL1iUktZA5Osc0ppEKaSleB13ThfNQ3XXcVKJn0JjVFONk0purUEykAjTsmb475Tinhynu2AL4e-x8vFJVteCyWM4Vwhff0fvYlLGvF2qKTWSiohUL26U0szQGunFAaXDvb-qxG8PYJ96OHwUOfMrhO0U2vXCdqv79eAujjqkGf486BdurWVFlrZH5-vrPleXV9u5U-7Ff8ASlyeaA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1847754533</pqid></control><display><type>article</type><title>Amniotic fluid discordance in monochorionic diamniotic twin pregnancies is associated with increased risk for twin anemia-polycythemia sequence</title><source>Wiley</source><creator>Hiersch, Liran ; Eitan, Mayan ; Ashwal, Eran ; Weisz, Boaz ; Chayen, Benny ; Lipitz, Shlomo ; Yinon, Yoav</creator><creatorcontrib>Hiersch, Liran ; Eitan, Mayan ; Ashwal, Eran ; Weisz, Boaz ; Chayen, Benny ; Lipitz, Shlomo ; Yinon, Yoav</creatorcontrib><description>Objective
To estimate the risk for twin anemia–polycythemia sequence (TAPS) and adverse perinatal outcome in monochorionic diamniotic (MCDA) twin pregnancies with amniotic fluid discordance (AFD).
Methods
Retrospective cohort study of 34 MCDA pregnancies with AFD (intertwin difference of ≥3 cm in maximal vertical pocket measurement) without meeting the criteria for twin to twin transfusion syndrome or selective intrauterine growth restriction. Perinatal outcome measures and the risk for TAPS were compared with a control group consisted of 101 MCDA twin pregnancies without AFD, twin to twin transfusion syndrome, or selective intrauterine growth restriction. Composite neonatal morbidity was defined as the presence of respiratory distress syndrome, intraventricular hemorrhage grades 3 and 4, necrotizing enterocolitis or sepsis.
Results
Overall, in the AFD group, seven twin pairs (20.6%) were complicated by TAPS compared with none in the controls (p < 0.001). In the AFD group, women who developed TAPS had significantly higher AFD compared with women who did not develop TAPS (7.3 cm vs 4.2 cm, p < 0.01). Patients in the AFD group delivered earlier (34.6 vs 35.8 weeks, p < 0.001) and had significantly higher rate of composite neonatal morbidity compared with the control group (13.2 vs 2.5%, p = 0.002).
Conclusions
Despite the overall favorable outcome, MCDA twins with AFD are at increased risk for developing TAPS. © 2016 John Wiley & Sons, Ltd.
What's already known about this topic?
The clinical significance of amniotic fluid discordance (AFD) without meeting the criteria for twin to twin transfusion syndrome (TTTS) is not clear.
What does this study adds?
Monochorionic diamniotic (MCDA) twin pregnancies complicated by AFD are at increased risk of early delivery as compared with uncomplicated MCDA twins.
The risk for twin anemia–polycythemia sequence (TAPS) was higher among MCDA twins with AFD, and this risk appeared to be related to the severity of AFD.</description><identifier>ISSN: 0197-3851</identifier><identifier>EISSN: 1097-0223</identifier><identifier>DOI: 10.1002/pd.4939</identifier><identifier>PMID: 27734505</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adult ; Amniotic Fluid - diagnostic imaging ; Anemia ; Case-Control Studies ; Cerebral Hemorrhage - epidemiology ; Enterocolitis, Necrotizing - epidemiology ; Female ; Fetofetal Transfusion - diagnosis ; Fetofetal Transfusion - diagnostic imaging ; Fetofetal Transfusion - epidemiology ; Health risk assessment ; Humans ; Infant, Newborn ; Male ; Neonatal Sepsis - epidemiology ; Oligohydramnios - diagnostic imaging ; Oligohydramnios - epidemiology ; Polyhydramnios - diagnostic imaging ; Polyhydramnios - epidemiology ; Pregnancy ; Pregnancy, Twin ; Respiratory Distress Syndrome, Newborn - epidemiology ; Retrospective Studies ; Twins ; Twins, Monozygotic ; Ultrasonography, Prenatal</subject><ispartof>Prenatal diagnosis, 2016-12, Vol.36 (12), p.1099-1103</ispartof><rights>2016 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3519-8c5047448e040fa557e396463188bac6bb17f60204c2eb95a4bb23fbac6e59eb3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27734505$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hiersch, Liran</creatorcontrib><creatorcontrib>Eitan, Mayan</creatorcontrib><creatorcontrib>Ashwal, Eran</creatorcontrib><creatorcontrib>Weisz, Boaz</creatorcontrib><creatorcontrib>Chayen, Benny</creatorcontrib><creatorcontrib>Lipitz, Shlomo</creatorcontrib><creatorcontrib>Yinon, Yoav</creatorcontrib><title>Amniotic fluid discordance in monochorionic diamniotic twin pregnancies is associated with increased risk for twin anemia-polycythemia sequence</title><title>Prenatal diagnosis</title><addtitle>Prenat Diagn</addtitle><description>Objective
To estimate the risk for twin anemia–polycythemia sequence (TAPS) and adverse perinatal outcome in monochorionic diamniotic (MCDA) twin pregnancies with amniotic fluid discordance (AFD).
Methods
Retrospective cohort study of 34 MCDA pregnancies with AFD (intertwin difference of ≥3 cm in maximal vertical pocket measurement) without meeting the criteria for twin to twin transfusion syndrome or selective intrauterine growth restriction. Perinatal outcome measures and the risk for TAPS were compared with a control group consisted of 101 MCDA twin pregnancies without AFD, twin to twin transfusion syndrome, or selective intrauterine growth restriction. Composite neonatal morbidity was defined as the presence of respiratory distress syndrome, intraventricular hemorrhage grades 3 and 4, necrotizing enterocolitis or sepsis.
Results
Overall, in the AFD group, seven twin pairs (20.6%) were complicated by TAPS compared with none in the controls (p < 0.001). In the AFD group, women who developed TAPS had significantly higher AFD compared with women who did not develop TAPS (7.3 cm vs 4.2 cm, p < 0.01). Patients in the AFD group delivered earlier (34.6 vs 35.8 weeks, p < 0.001) and had significantly higher rate of composite neonatal morbidity compared with the control group (13.2 vs 2.5%, p = 0.002).
Conclusions
Despite the overall favorable outcome, MCDA twins with AFD are at increased risk for developing TAPS. © 2016 John Wiley & Sons, Ltd.
What's already known about this topic?
The clinical significance of amniotic fluid discordance (AFD) without meeting the criteria for twin to twin transfusion syndrome (TTTS) is not clear.
What does this study adds?
Monochorionic diamniotic (MCDA) twin pregnancies complicated by AFD are at increased risk of early delivery as compared with uncomplicated MCDA twins.
The risk for twin anemia–polycythemia sequence (TAPS) was higher among MCDA twins with AFD, and this risk appeared to be related to the severity of AFD.</description><subject>Adult</subject><subject>Amniotic Fluid - diagnostic imaging</subject><subject>Anemia</subject><subject>Case-Control Studies</subject><subject>Cerebral Hemorrhage - epidemiology</subject><subject>Enterocolitis, Necrotizing - epidemiology</subject><subject>Female</subject><subject>Fetofetal Transfusion - diagnosis</subject><subject>Fetofetal Transfusion - diagnostic imaging</subject><subject>Fetofetal Transfusion - epidemiology</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Neonatal Sepsis - epidemiology</subject><subject>Oligohydramnios - diagnostic imaging</subject><subject>Oligohydramnios - epidemiology</subject><subject>Polyhydramnios - diagnostic imaging</subject><subject>Polyhydramnios - epidemiology</subject><subject>Pregnancy</subject><subject>Pregnancy, Twin</subject><subject>Respiratory Distress Syndrome, Newborn - epidemiology</subject><subject>Retrospective Studies</subject><subject>Twins</subject><subject>Twins, Monozygotic</subject><subject>Ultrasonography, Prenatal</subject><issn>0197-3851</issn><issn>1097-0223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNpd0c1u1DAQAGALgehSEG-ALHFBQil2bMfxsSq0IK2AQwGJi-U4E9ZtEgc70bJPwSsz0bY9cBqP5hv_DSEvOTvjjJXvpvZMGmEekQ1nRhesLMVjsmEc16JW_IQ8y_kGYV0a_ZSclFoLqZjakL_nwxjiHDzt-iW0tA3Zx9S60QMNIx3iGP0uphBHJG1w93reY3VK8GtEGiDTkKnLOfrgZmjpPsw77PcJXMY0hXxLu5iObW6EIbhiiv3BH-bdmtAMvxfAQ5-TJ53rM7y4i6fk2-WH64uPxfbL1aeL823hheKmqL1iUktZA5Osc0ppEKaSleB13ThfNQ3XXcVKJn0JjVFONk0purUEykAjTsmb475Tinhynu2AL4e-x8vFJVteCyWM4Vwhff0fvYlLGvF2qKTWSiohUL26U0szQGunFAaXDvb-qxG8PYJ96OHwUOfMrhO0U2vXCdqv79eAujjqkGf486BdurWVFlrZH5-vrPleXV9u5U-7Ff8ASlyeaA</recordid><startdate>201612</startdate><enddate>201612</enddate><creator>Hiersch, Liran</creator><creator>Eitan, Mayan</creator><creator>Ashwal, Eran</creator><creator>Weisz, Boaz</creator><creator>Chayen, Benny</creator><creator>Lipitz, Shlomo</creator><creator>Yinon, Yoav</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QP</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201612</creationdate><title>Amniotic fluid discordance in monochorionic diamniotic twin pregnancies is associated with increased risk for twin anemia-polycythemia sequence</title><author>Hiersch, Liran ; Eitan, Mayan ; Ashwal, Eran ; Weisz, Boaz ; Chayen, Benny ; Lipitz, Shlomo ; Yinon, Yoav</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3519-8c5047448e040fa557e396463188bac6bb17f60204c2eb95a4bb23fbac6e59eb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Amniotic Fluid - diagnostic imaging</topic><topic>Anemia</topic><topic>Case-Control Studies</topic><topic>Cerebral Hemorrhage - epidemiology</topic><topic>Enterocolitis, Necrotizing - epidemiology</topic><topic>Female</topic><topic>Fetofetal Transfusion - diagnosis</topic><topic>Fetofetal Transfusion - diagnostic imaging</topic><topic>Fetofetal Transfusion - epidemiology</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Neonatal Sepsis - epidemiology</topic><topic>Oligohydramnios - diagnostic imaging</topic><topic>Oligohydramnios - epidemiology</topic><topic>Polyhydramnios - diagnostic imaging</topic><topic>Polyhydramnios - epidemiology</topic><topic>Pregnancy</topic><topic>Pregnancy, Twin</topic><topic>Respiratory Distress Syndrome, Newborn - epidemiology</topic><topic>Retrospective Studies</topic><topic>Twins</topic><topic>Twins, Monozygotic</topic><topic>Ultrasonography, Prenatal</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hiersch, Liran</creatorcontrib><creatorcontrib>Eitan, Mayan</creatorcontrib><creatorcontrib>Ashwal, Eran</creatorcontrib><creatorcontrib>Weisz, Boaz</creatorcontrib><creatorcontrib>Chayen, Benny</creatorcontrib><creatorcontrib>Lipitz, Shlomo</creatorcontrib><creatorcontrib>Yinon, Yoav</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Prenatal diagnosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hiersch, Liran</au><au>Eitan, Mayan</au><au>Ashwal, Eran</au><au>Weisz, Boaz</au><au>Chayen, Benny</au><au>Lipitz, Shlomo</au><au>Yinon, Yoav</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amniotic fluid discordance in monochorionic diamniotic twin pregnancies is associated with increased risk for twin anemia-polycythemia sequence</atitle><jtitle>Prenatal diagnosis</jtitle><addtitle>Prenat Diagn</addtitle><date>2016-12</date><risdate>2016</risdate><volume>36</volume><issue>12</issue><spage>1099</spage><epage>1103</epage><pages>1099-1103</pages><issn>0197-3851</issn><eissn>1097-0223</eissn><abstract>Objective
To estimate the risk for twin anemia–polycythemia sequence (TAPS) and adverse perinatal outcome in monochorionic diamniotic (MCDA) twin pregnancies with amniotic fluid discordance (AFD).
Methods
Retrospective cohort study of 34 MCDA pregnancies with AFD (intertwin difference of ≥3 cm in maximal vertical pocket measurement) without meeting the criteria for twin to twin transfusion syndrome or selective intrauterine growth restriction. Perinatal outcome measures and the risk for TAPS were compared with a control group consisted of 101 MCDA twin pregnancies without AFD, twin to twin transfusion syndrome, or selective intrauterine growth restriction. Composite neonatal morbidity was defined as the presence of respiratory distress syndrome, intraventricular hemorrhage grades 3 and 4, necrotizing enterocolitis or sepsis.
Results
Overall, in the AFD group, seven twin pairs (20.6%) were complicated by TAPS compared with none in the controls (p < 0.001). In the AFD group, women who developed TAPS had significantly higher AFD compared with women who did not develop TAPS (7.3 cm vs 4.2 cm, p < 0.01). Patients in the AFD group delivered earlier (34.6 vs 35.8 weeks, p < 0.001) and had significantly higher rate of composite neonatal morbidity compared with the control group (13.2 vs 2.5%, p = 0.002).
Conclusions
Despite the overall favorable outcome, MCDA twins with AFD are at increased risk for developing TAPS. © 2016 John Wiley & Sons, Ltd.
What's already known about this topic?
The clinical significance of amniotic fluid discordance (AFD) without meeting the criteria for twin to twin transfusion syndrome (TTTS) is not clear.
What does this study adds?
Monochorionic diamniotic (MCDA) twin pregnancies complicated by AFD are at increased risk of early delivery as compared with uncomplicated MCDA twins.
The risk for twin anemia–polycythemia sequence (TAPS) was higher among MCDA twins with AFD, and this risk appeared to be related to the severity of AFD.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>27734505</pmid><doi>10.1002/pd.4939</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0197-3851 |
| ispartof | Prenatal diagnosis, 2016-12, Vol.36 (12), p.1099-1103 |
| issn | 0197-3851 1097-0223 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1835399115 |
| source | Wiley |
| subjects | Adult Amniotic Fluid - diagnostic imaging Anemia Case-Control Studies Cerebral Hemorrhage - epidemiology Enterocolitis, Necrotizing - epidemiology Female Fetofetal Transfusion - diagnosis Fetofetal Transfusion - diagnostic imaging Fetofetal Transfusion - epidemiology Health risk assessment Humans Infant, Newborn Male Neonatal Sepsis - epidemiology Oligohydramnios - diagnostic imaging Oligohydramnios - epidemiology Polyhydramnios - diagnostic imaging Polyhydramnios - epidemiology Pregnancy Pregnancy, Twin Respiratory Distress Syndrome, Newborn - epidemiology Retrospective Studies Twins Twins, Monozygotic Ultrasonography, Prenatal |
| title | Amniotic fluid discordance in monochorionic diamniotic twin pregnancies is associated with increased risk for twin anemia-polycythemia sequence |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T02%3A19%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Amniotic%20fluid%20discordance%20in%20monochorionic%20diamniotic%20twin%20pregnancies%20is%20associated%20with%20increased%20risk%20for%20twin%20anemia-polycythemia%20sequence&rft.jtitle=Prenatal%20diagnosis&rft.au=Hiersch,%20Liran&rft.date=2016-12&rft.volume=36&rft.issue=12&rft.spage=1099&rft.epage=1103&rft.pages=1099-1103&rft.issn=0197-3851&rft.eissn=1097-0223&rft_id=info:doi/10.1002/pd.4939&rft_dat=%3Cproquest_pubme%3E4275237131%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3519-8c5047448e040fa557e396463188bac6bb17f60204c2eb95a4bb23fbac6e59eb3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1847754533&rft_id=info:pmid/27734505&rfr_iscdi=true |