Tenofovir disoproxil fumarate (TDF) vs. emtricitabine (FTC)/TDF in lamivudine resistant hepatitis B: A 5-year randomised study

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Bibliographic Details
Published in:Journal of hepatology 2017-01, Vol.66 (1), p.11-18
Main Authors: Fung, Scott, Kwan, Peter, Fabri, Milotka, Horban, Andrzej, Pelemis, Mijomir, Hann, Hie-Won, Gurel, Selim, Caruntu, Florin A, Flaherty, John F, Massetto, Benedetta, Kim, Kyungpil, Kitrinos, Kathryn M, Subramanian, G. Mani, McHutchison, John G, Yee, Leland J, Elkhashab, Magdy, Berg, Thomas, Sporea, Ioan, Yurdaydin, Cihan, Husa, Petr, Jablkowski, Maciej S, Gane, Edward
Format: Article
Language:English
Subjects:
Adult
Alanine
Alanine transaminase
Antigens
Antiviral Agents - administration & dosage
Antiviral Agents - adverse effects
Antiviral drugs
Bone mineral density
Clinical trials
Deoxyribonucleic acid
DNA
DNA, Viral - blood
Double-Blind Method
Drug Monitoring
Drug Resistance, Viral
Drug therapy
Drug Therapy, Combination - methods
Emtricitabine
Emtricitabine - administration & dosage
Emtricitabine - adverse effects
Female
Gastroenterology and Hepatology
Hepatitis
Hepatitis B
Hepatitis B e antigen
Hepatitis B e Antigens - blood
Hepatitis B surface antigen
Hepatitis B Surface Antigens - blood
Hepatitis B virus - drug effects
Hepatitis B virus - isolation & purification
Hepatitis B virus - physiology
Hepatitis B, Chronic - drug therapy
Hepatitis B, Chronic - virology
Hip
Humans
Lamivudine
Lamivudine resistant
Male
Middle Aged
Patients
Renal function
Seroconversion
Spine
Tenofovir
Tenofovir - administration & dosage
Tenofovir - adverse effects
Tenofovir disoproxil fumarate
Treatment Outcome
Viral Load - drug effects
Viral suppression
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Description
Summary:Graphical abstract
ISSN:0168-8278
1600-0641
DOI:10.1016/j.jhep.2016.08.008