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Comparison of Donor Sources in Hematopoietic Stem Cell Transplantation for Childhood Acute Leukemia: A Nationwide Retrospective Study

Highlights • Outcomes for both unrelated bone marrow transplantation and unrelated cord blood transplantation are currently not statistically inferior to those of identical related bone marrow transplantation • Unrelated cord blood transplantation is useful option for patients with clinical urgent s...

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Published in:Biology of blood and marrow transplantation 2016-12, Vol.22 (12), p.2226-2234
Main Authors: Sakaguchi, Hirotoshi, Watanabe, Nobuhiro, Matsumoto, Kimikazu, Yabe, Hiromasa, Kato, Shunichi, Ogawa, Atsushi, Inagaki, Jiro, Goto, Hiroaki, Koh, Katsuyoshi, Yoshida, Nao, Kato, Keisuke, Cho, Yuko, Kosaka, Yoshiyuki, Takahashi, Yoshiyuki, Inoue, Masami, Kato, Koji, Atsuta, Yoshiko, Miyamura, Koichi
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container_issue 12
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container_title Biology of blood and marrow transplantation
container_volume 22
creator Sakaguchi, Hirotoshi
Watanabe, Nobuhiro
Matsumoto, Kimikazu
Yabe, Hiromasa
Kato, Shunichi
Ogawa, Atsushi
Inagaki, Jiro
Goto, Hiroaki
Koh, Katsuyoshi
Yoshida, Nao
Kato, Keisuke
Cho, Yuko
Kosaka, Yoshiyuki
Takahashi, Yoshiyuki
Inoue, Masami
Kato, Koji
Atsuta, Yoshiko
Miyamura, Koichi
description Highlights • Outcomes for both unrelated bone marrow transplantation and unrelated cord blood transplantation are currently not statistically inferior to those of identical related bone marrow transplantation • Unrelated cord blood transplantation is useful option for patients with clinical urgent situations • New strategies are needed to reduce early transplantation-related mortality after unrelated cord blood transplantation
doi_str_mv 10.1016/j.bbmt.2016.09.020
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subjects Adolescent
Alternative donor
Bone Marrow Transplantation - mortality
Child
Child, Preschool
Childhood acute leukemia
Cord Blood Stem Cell Transplantation - mortality
Hematology, Oncology and Palliative Medicine
Hematopoietic Stem Cell Transplantation - methods
Hematopoietic Stem Cell Transplantation - mortality
Histocompatibility
Humans
Infant
Infant, Newborn
Japan
Male
Myeloablative Agonists - therapeutic use
Nationwide study
Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Retrospective Studies
Survival Analysis
Transplantation Conditioning - methods
Unrelated Donors
title Comparison of Donor Sources in Hematopoietic Stem Cell Transplantation for Childhood Acute Leukemia: A Nationwide Retrospective Study
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