Highlighting the Versatility of the Tracerlab Synthesis Modules. Part 1: Fully Automated Production of [F]Labelled Radiopharmaceuticals using a Tracerlab FX(FN)

The field of radiochemistry is moving towards exclusive use of automated synthesis modules for production of clinical radiopharmaceutical doses. Such a move comes with many advantages, but also presents radiochemists with the challenge of re-configuring synthesis modules for production of radiopharm...

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Bibliographic Details
Published in:Journal of labelled compounds & radiopharmaceuticals 2011-05, Vol.54 (6), p.292-307
Main Authors: Shao, Xia, Hoareau, Raphaël, Hockley, Brian G, Tluczek, Louis J M, Henderson, Bradford D, Padgett, Henry C, Scott, Peter J H
Format: Article
Language:English
Online Access:Get full text
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Summary:The field of radiochemistry is moving towards exclusive use of automated synthesis modules for production of clinical radiopharmaceutical doses. Such a move comes with many advantages, but also presents radiochemists with the challenge of re-configuring synthesis modules for production of radiopharmaceuticals that require non-conventional radiochemistry whilst maintaining full automation. This review showcases the versatility of the Tracerlab FX(FN) synthesis module by presenting simple, fully automated methods for producing [(18)F]FLT, [(18)F]FAZA, [(18)F]MPPF, [(18)F]FEOBV, [(18)F]sodium fluoride, [(18)F]fluorocholine and [(18)F]SFB.
ISSN:1099-1344