Platelet function testing in cardiac surgery

SUMMARY Bleeding in cardiac surgery is known to cause increased morbidity and mortality. The rise in the use of anti‐platelet medication has led to an increase in the number of patients presenting for cardiac surgery with platelet dysfunction, who are at a heightened risk of bleeding. However, the e...

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Bibliographic Details
Published in:Transfusion medicine (Oxford, England) England), 2016-10, Vol.26 (5), p.319-329
Main Author: Agarwal, S.
Format: Article
Language:English
Subjects:
bleeding
Blood Loss, Surgical - prevention & control
Blood Platelets - metabolism
cardiac surgery
Cardiac Surgical Procedures
Humans
platelet function
Platelet Function Tests - instrumentation
Platelet Function Tests - methods
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Summary:SUMMARY Bleeding in cardiac surgery is known to cause increased morbidity and mortality. The rise in the use of anti‐platelet medication has led to an increase in the number of patients presenting for cardiac surgery with platelet dysfunction, who are at a heightened risk of bleeding. However, the extent of platelet inhibition is well known to differ among individuals. In the past few years, a number of point‐of‐care platelet function testing devices, which may be able to assess platelet reactivity, have entered the market. This review will examine the devices most commonly studied and the evidence surrounding their use in cardiac surgery and their effect on blood loss.
ISSN:0958-7578
1365-3148
DOI:10.1111/tme.12335