Synthesis of 3-Iodoquinolines by Copper-Catalyzed Tandem Annulation from Diaryliodoniums, Nitriles, and 1-Iodoalkynes

A novel method for the synthesis of 3‐iodoquinolines was developed by copper‐catalyzed tandem annulation from diaryliodoniums, nitriles, and 1‐iodoalkynes. It is a method that is characterized by the most convenient operation and wide molecular diversity.

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Bibliographic Details
Published in:Advanced synthesis & catalysis 2016-07, Vol.358 (14), p.2332-2339
Main Authors: Wang, Xuesong, Wang, Xingyong, Huang, Dayun, Liu, Chulong, Wang, Xinyan, Hu, Yuefei
Format: Article
Language:English
Subjects:
1-iodoalkynes
annulation
Catalysis
Chemical reactions
copper catalysts
iodoniums
Nitriles
Organic chemistry
Synthesis
synthesis of quinolones
tandem reactions
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Description
Summary:A novel method for the synthesis of 3‐iodoquinolines was developed by copper‐catalyzed tandem annulation from diaryliodoniums, nitriles, and 1‐iodoalkynes. It is a method that is characterized by the most convenient operation and wide molecular diversity.
ISSN:1615-4150
1615-4169
DOI:10.1002/adsc.201600081