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Nonstandard finite difference scheme for a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions
In this paper, we first propose a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions. Then, we consider the discretization of the model by using nonstandard finite difference scheme. It is then followed by the investigation of the global stability of th...
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Published in: | Computers & mathematics with applications (1987) 2016-08, Vol.72 (4), p.1013-1020 |
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creator | Yang, Yu Zhou, Jinling Ma, Xinsheng Zhang, Tonghua |
description | In this paper, we first propose a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions. Then, we consider the discretization of the model by using nonstandard finite difference scheme. It is then followed by the investigation of the global stability of the equilibria of the discrete model. Our study shows that if the basic reproduction number R0≤1, then the infection-free equilibrium is globally asymptotically stable; however if R0>1, then the infection equilibrium is globally asymptotically stable. Numerical simulations are presented to illustrate our theoretical results. |
doi_str_mv | 10.1016/j.camwa.2016.06.015 |
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Numerical simulations are presented to illustrate our theoretical results.</description><subject>Asymptotic properties</subject><subject>Cell-to-cell transmission</subject><subject>Computer simulation</subject><subject>Discretization</subject><subject>Dynamic models</subject><subject>Finite difference method</subject><subject>Global stability</subject><subject>Lyapunov function</subject><subject>Mathematical analysis</subject><subject>Mathematical models</subject><subject>Nonstandard finite difference</subject><subject>Viruses</subject><issn>0898-1221</issn><issn>1873-7668</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqNUU1vGyEQRVUq1Un7C3rh2Mu6fCwsPvQQRU1bKUou7RmxMMhY3iVlsKP8h_7osnbUYxVpBMPjDbyZR8hHztaccf15t_ZuenJr0Q5r1oKrN2TFzSC7QWtzQVbMbEzHheDvyCXijjHWS8FW5M99nrG6ObgSaExzqkBDihEKzB4o-i1MQGMu1J3wA6Yj0KdUt2nuthkrPaZyQBqeZzclj3TKAfYnAh1zW07XXc2dh_2eto_okvwDanEzTgkxNR3vydvo9ggfXvYr8uv268-b793dw7cfN9d3nZd6U7tRDD0IrbnXTPnBD9w7Ex2XUXgjQZkhNEj1orXoFahRGCZGPfRRhrGPG3lFPp3ffSz59wGw2qZgkeNmyAe03EiljGb8NVQxbGQbrGxUeab6khELRPtY0uTKs-XMLjbZnT3ZZBebLGvBVav6cq6C1vAxQbHo0zL7kAr4akNO_63_C0nOnsg</recordid><startdate>201608</startdate><enddate>201608</enddate><creator>Yang, Yu</creator><creator>Zhou, Jinling</creator><creator>Ma, Xinsheng</creator><creator>Zhang, Tonghua</creator><general>Elsevier Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7SC</scope><scope>7TB</scope><scope>8FD</scope><scope>FR3</scope><scope>JQ2</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope></search><sort><creationdate>201608</creationdate><title>Nonstandard finite difference scheme for a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions</title><author>Yang, Yu ; Zhou, Jinling ; Ma, Xinsheng ; Zhang, Tonghua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c369t-b274e2661c605c7c71ca8fa13f2c83e587d71c542432c5e5b2802b674f3db4f93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Asymptotic properties</topic><topic>Cell-to-cell transmission</topic><topic>Computer simulation</topic><topic>Discretization</topic><topic>Dynamic models</topic><topic>Finite difference method</topic><topic>Global stability</topic><topic>Lyapunov function</topic><topic>Mathematical analysis</topic><topic>Mathematical models</topic><topic>Nonstandard finite difference</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Yu</creatorcontrib><creatorcontrib>Zhou, Jinling</creatorcontrib><creatorcontrib>Ma, Xinsheng</creatorcontrib><creatorcontrib>Zhang, Tonghua</creatorcontrib><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><jtitle>Computers & mathematics with applications (1987)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Yu</au><au>Zhou, Jinling</au><au>Ma, Xinsheng</au><au>Zhang, Tonghua</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nonstandard finite difference scheme for a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions</atitle><jtitle>Computers & mathematics with applications (1987)</jtitle><date>2016-08</date><risdate>2016</risdate><volume>72</volume><issue>4</issue><spage>1013</spage><epage>1020</epage><pages>1013-1020</pages><issn>0898-1221</issn><eissn>1873-7668</eissn><abstract>In this paper, we first propose a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions. 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subjects | Asymptotic properties Cell-to-cell transmission Computer simulation Discretization Dynamic models Finite difference method Global stability Lyapunov function Mathematical analysis Mathematical models Nonstandard finite difference Viruses |
title | Nonstandard finite difference scheme for a diffusive within-host virus dynamics model with both virus-to-cell and cell-to-cell transmissions |
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