Loading…
Prevalence and clinical correlates of flunitrazepam‐related complex sleep behaviors
Aim Complex sleep behaviors (CSB) are often associated with the use of hypnotic drugs. This study investigated the prevalence and correlates of CSB among psychiatric patients who were given flunitrazepam. Methods From June 2011 to May 2012, a total of 268 psychiatric outpatients who had received flu...
Saved in:
Published in: | Psychiatry and clinical neurosciences 2017-03, Vol.71 (3), p.198-203 |
---|---|
Main Authors: | , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | Aim
Complex sleep behaviors (CSB) are often associated with the use of hypnotic drugs. This study investigated the prevalence and correlates of CSB among psychiatric patients who were given flunitrazepam.
Methods
From June 2011 to May 2012, a total of 268 psychiatric outpatients who had received flunitrazepam for at least 3 months were enrolled. Data on occurrence of CSB, demographic characteristics, flunitrazepam dosage and duration of use, psychiatric diagnoses, physical illnesses, and alcohol use were collected. Logistic regression analysis was used to examine the clinical correlates of CSB.
Results
Sixty‐six participants (24.6%) reported experiencing CSB. Logistic regression analysis showed that a high dosage (>2 mg/day) of flunitrazepam (odds ratio [OR] = 1.941, 95% confidence interval [CI] = 1.090–3.455, P = 0.024) and alcohol use (OR = 1.948, 95%CI = 1.023–3.709, P = 0.042) were significantly associated with the occurrence of CSB. Sex, age, duration of flunitrazepam use, psychiatric diagnoses, and physical illnesses were not significantly associated with the occurrence of CSB.
Conclusion
CSB among flunitrazepam users should be monitored routinely, especially among those receiving a high dosage who also consume alcohol. |
---|---|
ISSN: | 1323-1316 1440-1819 |
DOI: | 10.1111/pcn.12472 |