Biennial lung cancer screening in Canada with smoking cessation—outcomes and cost-effectiveness

Highlights • Lung cancer screening by CT decreases mortality but consumes resources. • Our model suggests that biennial screening is more cost-effective than annual. • Over a 20 year screening program, quality-adjusted life-years saved are similar. • Average incremental CT scan use with biennial scr...

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Bibliographic Details
Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2016-11, Vol.101, p.98-103
Main Authors: Goffin, John R., MD, FRCPC, Flanagan, William M., BM, Miller, Anthony B., MD, FRCPC, Fitzgerald, Natalie R., MA, Memon, Saima, MBBS, MPH, Wolfson, Michael C., PhD, Evans, William K., MD, FRCPC
Format: Article
Language:English
Subjects:
Aged
Canada - epidemiology
Cost-Benefit Analysis - economics
Cost-effectiveness
Early Detection of Cancer - methods
Female
Hematology, Oncology and Palliative Medicine
Humans
Low-dose CT
Lung cancer
Lung Neoplasms - diagnostic imaging
Lung Neoplasms - economics
Lung Neoplasms - prevention & control
Male
Mass Screening - economics
Mass Screening - methods
Middle Aged
Pulmonary/Respiratory
Quality of Life
Quality-Adjusted Life Years
Radiation Dosage
Screening
Smoking - adverse effects
Smoking - epidemiology
Smoking cessation
Smoking Cessation - economics
Smoking Cessation - methods
Smoking Prevention
Tomography, X-Ray Computed - economics
Tomography, X-Ray Computed - methods
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Summary:Highlights • Lung cancer screening by CT decreases mortality but consumes resources. • Our model suggests that biennial screening is more cost-effective than annual. • Over a 20 year screening program, quality-adjusted life-years saved are similar. • Average incremental CT scan use with biennial screening is half that of annual. • Adding a smoking cessation program to screening improves cost-effectiveness.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2016.09.013