Characterization of Atherosclerotic Disease in Thoracic Aorta: A 3D, Multicontrast Vessel Wall Imaging Study

Abstract Purpose To investigate the characteristics of plaque in the thoracic aorta using three dimensional multicontrast magnetic resonance imaging. Materials and Methods Elderly subjects (≥60 years) were recruited in this study. Thoracic aorta was imaged on a 3.0T MR scanner by acquiring multicont...

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Bibliographic Details
Published in:European journal of radiology 2016-11, Vol.85 (11), p.2030-2035
Main Authors: Zhou, Changwu, MD, Qia, Huiyu, BS, He, Le, MD, Yuan, Chun, PhD, Chen, Huijun, PhD, Zhang, Qiang, BS, Li, Rui, PhD, Wang, Wei, MD, Du, Fang, MD, Li, Cheng, MD, Zhao, Xihai, MD, PhD
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aorta, Thoracic - diagnostic imaging
Aorta, Thoracic - pathology
Atherosclerosis
Atherosclerosis - diagnostic imaging
Atherosclerosis - pathology
Female
Humans
Imaging, Three-Dimensional - methods
Magnetic resonance imaging
Magnetic Resonance Imaging - instrumentation
Magnetic Resonance Imaging - methods
Male
Pilot Projects
Plaque, Atherosclerotic - diagnostic imaging
Plaque, Atherosclerotic - pathology
Radiology
Reproducibility of Results
Thoracic aorta
Vessel wall
Vulnerable plaque
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Summary:Abstract Purpose To investigate the characteristics of plaque in the thoracic aorta using three dimensional multicontrast magnetic resonance imaging. Materials and Methods Elderly subjects (≥60 years) were recruited in this study. Thoracic aorta was imaged on a 3.0T MR scanner by acquiring multicontrast sequences. The plaque burden was evaluated by measuring lumen area, wall area, wall thickness, and normalized wall index. The presence or absence of plaque and intraplaque hemorrhage (IPH)/mural thrombus (MT) were identified. The characteristics of atherosclerosis among different thoracic aorta segments (AAO: ascending aorta; AOA: aortic arch, and DOA: descending aorta) were determined. Results Of 66 recruited subjects (mean age 72.3 ± 6.2 years, 30 males), 55 (83.3%) had plaques in the thoracic aorta. The prevalence of plaque in AAO, AOA, and DAO was 5.4%, 72.7%, and 71.2%, respectively. In addition, 21.2% of subjects were found to have lesions with IPH/MT in the thoracic aorta. The prevalence of IPH/MT in segment of AAO, AOA and DAO was 0%, 13.6%, and 12.1%, respectively. The aortic wall showed the highest NWI in DAO (34.1% ± 4.8%), followed by AOA (31.2% ± 5%), and AAO (26.8% ± 3.3%) (p
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2016.09.006