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Lysosomal Membrane Stability and Metallothioneins in Digestive Gland of Mussels ( Mytilus galloprovincialis Lam.) as Biomarkers in a Field Study
The lysosomal membrane destabilization and the metallothionein content in the digestive gland cells of mussels ( Mytilus galloprovincialis Lam.), collected along the east coast of the North Adriatic (Istrian and Kvarnerine coast, Croatia), were examined over a period of four years (1996–1999). The l...
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| Published in: | Marine pollution bulletin 2001-12, Vol.42 (12), p.1373-1378 |
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| cites | cdi_FETCH-LOGICAL-c488t-e775626be04f58c6f0ecb5a663be341ca2cc537430726188d0c5abe8583d6a553 |
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| container_title | Marine pollution bulletin |
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| creator | Petrović, S Ozretić, B Krajnović-Ozretić, M Bobinac, D |
| description | The lysosomal membrane destabilization and the metallothionein content in the digestive gland cells of mussels (
Mytilus galloprovincialis Lam.), collected along the east coast of the North Adriatic (Istrian and Kvarnerine coast, Croatia), were examined over a period of four years (1996–1999). The lysosomal membrane stability, as a biomarker of general stress, showed that the membrane labilization period in mussels from polluted, urban- and industrial-related areas was significantly decreased (
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| doi_str_mv | 10.1016/S0025-326X(01)00167-9 |
| format | article |
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Mytilus galloprovincialis Lam.), collected along the east coast of the North Adriatic (Istrian and Kvarnerine coast, Croatia), were examined over a period of four years (1996–1999). The lysosomal membrane stability, as a biomarker of general stress, showed that the membrane labilization period in mussels from polluted, urban- and industrial-related areas was significantly decreased (
p<0.05) when compared to mussels from control, clean sea water sites. In the harbour of Rijeka, the most contaminated site, the lysosomal membrane stability was reduced by more than 70% compared to the control. This method also proved to be a useful biomarker for detection of additional stress caused by short-term hypoxia that occurred once during this study inside the polluted and periodically quite eutrophic Pula Harbour. The concentration of metallothioneins in the mussel digestive gland, as a specific biomarker of exposure to heavy metals, did not reveal significant differences (
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Mytilus galloprovincialis Lam.), collected along the east coast of the North Adriatic (Istrian and Kvarnerine coast, Croatia), were examined over a period of four years (1996–1999). The lysosomal membrane stability, as a biomarker of general stress, showed that the membrane labilization period in mussels from polluted, urban- and industrial-related areas was significantly decreased (
p<0.05) when compared to mussels from control, clean sea water sites. In the harbour of Rijeka, the most contaminated site, the lysosomal membrane stability was reduced by more than 70% compared to the control. This method also proved to be a useful biomarker for detection of additional stress caused by short-term hypoxia that occurred once during this study inside the polluted and periodically quite eutrophic Pula Harbour. The concentration of metallothioneins in the mussel digestive gland, as a specific biomarker of exposure to heavy metals, did not reveal significant differences (
p<0.05) between sites covered by this study.</description><subject>Adriatic Sea</subject><subject>Animal, plant and microbial ecology</subject><subject>Animals</subject><subject>Applied ecology</subject><subject>Biological and medical sciences</subject><subject>Biomarkers</subject><subject>biomonitoring</subject><subject>Bivalvia - physiology</subject><subject>Croatia</subject><subject>Digestion</subject><subject>digestive gland</subject><subject>Digestive System Physiological Phenomena</subject><subject>Ecotoxicology, biological effects of pollution</subject><subject>Effects of pollution and side effects of pesticides on protozoa and invertebrates</subject><subject>Environmental Monitoring</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>lysosomal membrane stability</subject><subject>Lysosomes - physiology</subject><subject>Membranes</subject><subject>metallothionein</subject><subject>Metallothionein - metabolism</subject><subject>metallothioneins</subject><subject>mussels</subject><subject>Mytilus galloprovincialis</subject><subject>North Adriatic</subject><subject>Oxidative Stress</subject><subject>Water Pollutants, Chemical - metabolism</subject><issn>0025-326X</issn><issn>1879-3363</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNqFkc9u1DAQxi0EokvhEUC-gNpDih2vHe-pgkIL0q44FCRuluNMyoCTFE-yUt6CR8b7R_TIydboNzPffB9jL6W4kEKat7dClLpQpfl-JuS5yKWqWD1iC2mrVaGUUY_Z4h9ywp4R_RRCVGUln7ITKW3-lHrB_qxnGmjofOQb6Orke-C3o68x4jhz3ze5PPoYh_EHDj1gTxx7_gHvgEbcAr-JO2Zo-WYigkj8jG_mEeNE_G7Xdp-GLfYBfUTia99dnHNP_D3mjekXpP00z68RYpP3Ts38nD1pfSR4cXxP2bfrj1-vPhXrLzefr96ti7C0diygqrQpTQ1i2WobTCsg1Nobo2pQSxl8GYJW1VLlk420thFB-xqstqoxXmt1yt4c5maFv6d8jeuQAsR8DwwTOWmVESurMqgPYEgDUYLW3SfM6mcnhdtF4fZRuJ3PTki3j8Ktct-r44Kp7qB56Dp6n4HXR8BT8LHN3gekB06pytrSZu7ywGV7YYuQHAWEPkCDCcLomgH_I-UvU32nVw</recordid><startdate>20011201</startdate><enddate>20011201</enddate><creator>Petrović, S</creator><creator>Ozretić, B</creator><creator>Krajnović-Ozretić, M</creator><creator>Bobinac, D</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QH</scope><scope>7TN</scope><scope>7TV</scope><scope>7U7</scope><scope>7UA</scope><scope>C1K</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope></search><sort><creationdate>20011201</creationdate><title>Lysosomal Membrane Stability and Metallothioneins in Digestive Gland of Mussels ( Mytilus galloprovincialis Lam.) as Biomarkers in a Field Study</title><author>Petrović, S ; Ozretić, B ; Krajnović-Ozretić, M ; Bobinac, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c488t-e775626be04f58c6f0ecb5a663be341ca2cc537430726188d0c5abe8583d6a553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adriatic Sea</topic><topic>Animal, plant and microbial ecology</topic><topic>Animals</topic><topic>Applied ecology</topic><topic>Biological and medical sciences</topic><topic>Biomarkers</topic><topic>biomonitoring</topic><topic>Bivalvia - physiology</topic><topic>Croatia</topic><topic>Digestion</topic><topic>digestive gland</topic><topic>Digestive System Physiological Phenomena</topic><topic>Ecotoxicology, biological effects of pollution</topic><topic>Effects of pollution and side effects of pesticides on protozoa and invertebrates</topic><topic>Environmental Monitoring</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>lysosomal membrane stability</topic><topic>Lysosomes - physiology</topic><topic>Membranes</topic><topic>metallothionein</topic><topic>Metallothionein - metabolism</topic><topic>metallothioneins</topic><topic>mussels</topic><topic>Mytilus galloprovincialis</topic><topic>North Adriatic</topic><topic>Oxidative Stress</topic><topic>Water Pollutants, Chemical - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Petrović, S</creatorcontrib><creatorcontrib>Ozretić, B</creatorcontrib><creatorcontrib>Krajnović-Ozretić, M</creatorcontrib><creatorcontrib>Bobinac, D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aqualine</collection><collection>Oceanic Abstracts</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><jtitle>Marine pollution bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Petrović, S</au><au>Ozretić, B</au><au>Krajnović-Ozretić, M</au><au>Bobinac, D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lysosomal Membrane Stability and Metallothioneins in Digestive Gland of Mussels ( Mytilus galloprovincialis Lam.) as Biomarkers in a Field Study</atitle><jtitle>Marine pollution bulletin</jtitle><addtitle>Mar Pollut Bull</addtitle><date>2001-12-01</date><risdate>2001</risdate><volume>42</volume><issue>12</issue><spage>1373</spage><epage>1378</epage><pages>1373-1378</pages><issn>0025-326X</issn><eissn>1879-3363</eissn><coden>MPNBAZ</coden><abstract>The lysosomal membrane destabilization and the metallothionein content in the digestive gland cells of mussels (
Mytilus galloprovincialis Lam.), collected along the east coast of the North Adriatic (Istrian and Kvarnerine coast, Croatia), were examined over a period of four years (1996–1999). The lysosomal membrane stability, as a biomarker of general stress, showed that the membrane labilization period in mussels from polluted, urban- and industrial-related areas was significantly decreased (
p<0.05) when compared to mussels from control, clean sea water sites. In the harbour of Rijeka, the most contaminated site, the lysosomal membrane stability was reduced by more than 70% compared to the control. This method also proved to be a useful biomarker for detection of additional stress caused by short-term hypoxia that occurred once during this study inside the polluted and periodically quite eutrophic Pula Harbour. The concentration of metallothioneins in the mussel digestive gland, as a specific biomarker of exposure to heavy metals, did not reveal significant differences (
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| ispartof | Marine pollution bulletin, 2001-12, Vol.42 (12), p.1373-1378 |
| issn | 0025-326X 1879-3363 |
| language | eng |
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| source | ScienceDirect Journals |
| subjects | Adriatic Sea Animal, plant and microbial ecology Animals Applied ecology Biological and medical sciences Biomarkers biomonitoring Bivalvia - physiology Croatia Digestion digestive gland Digestive System Physiological Phenomena Ecotoxicology, biological effects of pollution Effects of pollution and side effects of pesticides on protozoa and invertebrates Environmental Monitoring Fundamental and applied biological sciences. Psychology lysosomal membrane stability Lysosomes - physiology Membranes metallothionein Metallothionein - metabolism metallothioneins mussels Mytilus galloprovincialis North Adriatic Oxidative Stress Water Pollutants, Chemical - metabolism |
| title | Lysosomal Membrane Stability and Metallothioneins in Digestive Gland of Mussels ( Mytilus galloprovincialis Lam.) as Biomarkers in a Field Study |
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