In-Hospital Mortality in Patients with Periprosthetic Joint Infection

Abstract Introduction While periprosthetic joint infection (PJI) has a huge impact on patient function and health, only a few studies have investigated its impact on mortality. The purpose of this large-scale study was to 1) determine the rate and trends of in-hospital mortality for PJI and 2) compa...

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Bibliographic Details
Published in:The Journal of arthroplasty 2017-03, Vol.32 (3), p.948-952.e1
Main Authors: Shahi, Alisina, MD, Tan, Timothy L., MD, Chen, Antonia F., MD, MBA, Maltenfort, Mitchell G., PhD, Parvizi, Javad, MD FRCS
Format: Article
Language:English
Subjects:
Aged
Arthroplasty, Replacement, Hip - adverse effects
Arthroplasty, Replacement, Knee - adverse effects
Comorbidity
complications
Female
Hospital Mortality
Hospitalization
Humans
in-hospital mortality
Infection Control
Male
Middle Aged
Odds Ratio
Orthopedics
periprosthetic joint infection
Prosthesis-Related Infections - etiology
Prosthesis-Related Infections - mortality
Reoperation - mortality
Retrospective Studies
Risk
total hip arthroplasty
total joint arthroplasty
total knee arthroplasty
United States - epidemiology
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Summary:Abstract Introduction While periprosthetic joint infection (PJI) has a huge impact on patient function and health, only a few studies have investigated its impact on mortality. The purpose of this large-scale study was to 1) determine the rate and trends of in-hospital mortality for PJI and 2) compare the in-hospital mortality rate of patients with PJI and those undergoing revision arthroplasty for aseptic failure and patients undergoing other non-orthopedic major surgical procedures. Methods Data from the Nationwide Inpatient Sample (NIS) from 2002 to 2010 were analyzed to determine the risk of in-hospital mortality for PJI patients compared with aseptic revision arthroplasty. The Elixhauser comorbidity index was used to obtain patient comorbidities. Multiple logistic regression analyses were used to examine if PJI and other patient-related factors were associated with mortality. Results PJI was associated with an increased risk (odds ratio [OR] 2.05, p
ISSN:0883-5403
1532-8406
DOI:10.1016/j.arth.2016.09.027