Patterns and Predictors of Freezing of Gait Improvement Following Rasagiline Therapy: A Pilot Study

Highlights • Freezing of gait (FoG) is a challenging clinical symptom in Parkinson’s disease. • Heterogeneous response to treatment with rasagiline is common. • We explored the clinical variables that may predict improvement. • We identified objective and subjective FOG measures with good explanator...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2016-11, Vol.150, p.117-124
Main Authors: Rahimi, Fariborz, Roberts, Angela C, Jog, Mandar
Format: Article
Language:English
Subjects:
Aged
Anxiety
Female
Freezing of gait
Gait Disorders, Neurologic - drug therapy
Gait Disorders, Neurologic - etiology
Humans
Indans - administration & dosage
Indans - pharmacology
Inventory
Male
Middle Aged
Monoamine Oxidase Inhibitors - administration & dosage
Monoamine Oxidase Inhibitors - pharmacology
Neurology
Neurosurgery
Outcome Assessment (Health Care)
Parkinson Disease - complications
Parkinson Disease - drug therapy
Parkinson's disease
Patients
Pilot Projects
Rasagaline
Studies
Treatment
Variability
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Description
Summary:Highlights • Freezing of gait (FoG) is a challenging clinical symptom in Parkinson’s disease. • Heterogeneous response to treatment with rasagiline is common. • We explored the clinical variables that may predict improvement. • We identified objective and subjective FOG measures with good explanatory power.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2016.08.025