Longitudinal assessment of subcortical gray matter volume, cortical thickness, and white matter integrity in HIV-positive patients

Purpose To longitudinally evaluate the cortical thickness and deep gray matter structures volume, measured from T1 three‐dimensional (3D) Gradient echo‐weighted imaging, and white matter integrity, assessed from diffusion tensor imaging (DTI) of HIV‐positive patients. Materials and Methods Twenty‐on...

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Bibliographic Details
Published in:Journal of magnetic resonance imaging 2016-11, Vol.44 (5), p.1262-1269
Main Authors: Corrêa, Diogo Goulart, Zimmermann, Nicolle, Tukamoto, Gustavo, Doring, Thomas, Ventura, Nina, Leite, Sarah C.B., Cabral, Rafael Ferracini, Fonseca, Rochele Paz, Bahia, Paulo R.V., Gasparetto, Emerson Leandro
Format: Article
Language:English
Subjects:
Abnormalities
Adult
Anisotropy
Antiretroviral agents
Antiretroviral drugs
Antiretroviral Therapy, Highly Active - methods
CD4 antigen
Cortex
cortical thickness
Dementia disorders
diffusion tensor imaging
Diffusion Tensor Imaging - methods
Diffusivity
Dimensional measurement
Encephalitis, Viral - drug therapy
Encephalitis, Viral - immunology
Encephalitis, Viral - pathology
Female
Gray Matter - immunology
Gray Matter - pathology
Highly active antiretroviral therapy
HIV
HIV Infections - drug therapy
HIV Infections - immunology
HIV Infections - pathology
HIV-associated neurocognitive disorders
Human immunodeficiency virus
Humans
Image processing
Image segmentation
Integrity
Lentivirus
longitudinal follow-up
Longitudinal Studies
Lymphocytes
Lymphocytes T
Magnetic resonance imaging
Magnetization
Male
Middle Aged
NMR
Nuclear magnetic resonance
Organ Size - immunology
Patients
Permutations
Reconstruction
Resonance
Retroviridae
Spatial analysis
Statistical analysis
Substantia alba
Substantia grisea
Therapy
Thickness
Treatment Outcome
Viral Load - immunology
White Matter - immunology
White Matter - pathology
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Summary:Purpose To longitudinally evaluate the cortical thickness and deep gray matter structures volume, measured from T1 three‐dimensional (3D) Gradient echo‐weighted imaging, and white matter integrity, assessed from diffusion tensor imaging (DTI) of HIV‐positive patients. Materials and Methods Twenty‐one HIV‐positive patients on stable highly active antiretroviral therapy (HAART) with CD4+ T lymphocytes count >200 cells/mL and viral load
ISSN:1053-1807
1522-2586
DOI:10.1002/jmri.25263