Combined Approaches to the Skull Base for Intracranial Extension of Tumors via Perineural Spread Can Improve Patient Outcomes

Highlights • Perineural tumor spread in head and neck carcinoma represents a poor prognosis. • Surgery for perineural spread can markedly improve symptoms and quality of life. • Aggressive and combined approaches can improve both morbidity and mortality.

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2016-11, Vol.150, p.46-53
Main Authors: Palejwala, Sheri K., MD, Barry, Jonnae Y., MD, Rodriguez, Crystal N., BS, Parikh, Chandni A., MS, Goldstein, Stephen A., MD, Lemole, G. Michael, MD
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Brain Neoplasms - mortality
Brain Neoplasms - surgery
Chemotherapy
Child, Preschool
Cranial Nerve Neoplasms - mortality
Cranial Nerve Neoplasms - surgery
Cranial nerve neuropathy
Decision making
Endoscopy
Female
Head and neck carcinoma
Humans
Male
Medical prognosis
Middle Aged
Mortality
Neurology
Neurosurgery
Neurosurgical Procedures - methods
NMR
Nuclear magnetic resonance
Outcome Assessment (Health Care)
Pain
Patients
Perineural spread
Radiation therapy
Retrospective Studies
Skull base tumors
Skull Neoplasms - mortality
Skull Neoplasms - surgery
Surgical approaches
Tumors
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Description
Summary:Highlights • Perineural tumor spread in head and neck carcinoma represents a poor prognosis. • Surgery for perineural spread can markedly improve symptoms and quality of life. • Aggressive and combined approaches can improve both morbidity and mortality.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2016.08.029